In this study, we performed the first transcriptional profiling of macrodactyly tissue.
Frank H Lau, Fang Xia, Adam Kaplan, Felecia Cerrato, Arin K Greene, Amir Taghinia,Chad A Cowan, Brian I Labow 2012, 'Expression analysis of macrodactyly identifies pleiotrophin upregulation.', PLoS ONEhttp://europepmc.org/articles/PMC3407187?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To date, no genes or loci have been implicated in the development of macrodactyly.
Frank H Lau, Fang Xia, Adam Kaplan, Felecia Cerrato, Arin K Greene, Amir Taghinia,Chad A Cowan, Brian I Labow 2012, 'Expression analysis of macrodactyly identifies pleiotrophin upregulation.', PLoS ONEhttp://europepmc.org/articles/PMC3407187?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To our knowledge, only a few cases regarding adults with macrodactyly of the foot have been reported in the literature.
Celalettin Sever, Cihan Sahin, Yalcin Bayram, Safak Ekinci, Bilge Kaan Aysal, UfukBerber, Mehmet Incedayi, Fatih Uygur, Yalcin Kulahci 2014, 'Adult Foot Macrodactyly: A Case Report and Review of the Literature', Archives of Clinical and Experimental Surgeryhttp://www.scopemed.org/fulltextpdf.php?mno=20884. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We advocate early surgical treatment of macrodactyly of the foot to enhance the quality of social life.
Celalettin Sever, Cihan Sahin, Yalcin Bayram, Safak Ekinci, Bilge Kaan Aysal, UfukBerber, Mehmet Incedayi, Fatih Uygur, Yalcin Kulahci 2014, 'Adult Foot Macrodactyly: A Case Report and Review of the Literature', Archives of Clinical and Experimental Surgeryhttp://www.scopemed.org/fulltextpdf.php?mno=20884. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)