an immunoglobulin of unusually high relative molecular mass, observed in the blood in some diseases
2. Also called: immunoglobulin M
the normal form of this immunoglobulin
Examples of 'macroglobulin' in a sentence
macroglobulin
Procalcitonin, fibrinogen, α-2-macroglobulin and tissue plasminogen activator were not significantly differentacross groups.
Leena B Mithal, Hannah L Palac, Ram Yogev, Linda M Ernst, Karen K Mestan 2017, 'Cord Blood Acute Phase Reactants Predict Early Onset Neonatal Sepsis in Preterm Infants.',PLoS ONEhttp://europepmc.org/articles/PMC5207723?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Several studies indicate that α-2-macroglobulin levels are elevated in diabetic patients.
Juan Pablo Aitken, Carolina Ortiz, Irene Morales-Bozo, Gonzalo Rojas-Alcayaga, MauricioBaeza, Caroll Beltran, Alejandro Escobar 2015, 'α-2-Macroglobulin in Saliva Is Associated with Glycemic Control in Patients with Type2 Diabetes Mellitus', Disease Markershttp://dx.doi.org/10.1155/2015/128653. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The proteins were α-1-macroglobulin, amyloid precursor-like protein 1, keratin 16, orosomucoid 2 and pigment epithelium-derived factor.
Baraniuk James N, Casado Begona, Maibach Hilda, Clauw Daniel J, Pannell Lewis K, HessS Sonja 2005, 'A chronic fatigue syndrome – related proteome in human cerebrospinal fluid', BMC Neurologyhttp://www.biomedcentral.com/1471-2377/5/22. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Other components were carbonic anhydrase, collagens, echinonectin, a α2-macroglobulin-like protein and several proteinscontaining scavenger receptor cysteine-rich domains.
Mann Karlheinz, Poustka Albert J, Mann Matthias 2008, 'The sea urchin (Strongylocentrotus purpuratus) test and spine proteomes',Proteome Sciencehttp://www.proteomesci.com/content/6/1/22. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)