a membrane protein that transports substances across cell membranes
Examples of 'antiporter' in a sentence
antiporter
The sodium-independent cystine-glutamate antiporter plays an important role in extracellular cystine uptake.
Masaki Nagane, Eiichi Kanai, Yuki Shibata, Takuto Shimizu, Chie Yoshioka, Takuya Maruo,Tadashi Yamashita 2018, 'Sulfasalazine, an inhibitor of the cystine-glutamate antiporter, reduces DNA damagerepair and enhances radiosensitivity in murine B16F10 melanoma', PLOS ONE10.1371/journal.pone.0195151. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The recombinant antiporter was functional in vivo and in vitro.
Christopher J Lentes, Syed H Mir, Marc Boehm, Constanta Ganea, Klaus Fendler, CarolaHunte 2014, 'Molecular characterization of the Na+/H+-antiporter NhaA from Salmonella Typhimurium.',PLoS ONEhttp://europepmc.org/articles/PMC4092016?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The glutamate/cystine antiporter system xc– connects the antioxidant defense with neurotransmission and behaviour.
Chi-Huang Chang, Hua-Xin Chen, George Yü, Chiung-Chi Peng, Robert Y. Peng 2014, 'Curcumin-Protected PC12 Cells Against Glutamate-Induced Oxidative Toxicity', Food Technology and Biotechnologyhttp://hrcak.srce.hr/file/193457. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In addition, glutamate accumulation can also inhibit cystine uptake by reversing the action of the cystine/glutamate antiporter.
Aristeidis eKritis, Eleni eStamoula, Krystallenia ePaniskaki, Theofanis eVavilis 2015, 'Researching glutamate – induced cytotoxicity in different cell lines: a comparative/,collective analysis/study', Frontiers in Cellular Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fncel.2015.00091/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The addition of nitrite before nitrate had no effect, suggesting no role for a nitrate/nitrite antiporter.
Michelle M Giffin, Ronald W Raab, Melissa Morganstern, Charles D Sohaskey 2012, 'Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacteriumtuberculosis.', PLoS ONEhttp://europepmc.org/articles/PMC3445494?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Reversal of the antiporter action reinforces the aforementioned events by depleting neurons of cysteine and eventually glutathione's reducing potential.
Aristeidis eKritis, Eleni eStamoula, Krystallenia ePaniskaki, Theofanis eVavilis 2015, 'Researching glutamate – induced cytotoxicity in different cell lines: a comparative/,collective analysis/study', Frontiers in Cellular Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fncel.2015.00091/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)