[1715–25; anti- + scorbutic]This word is first recorded in the period 1715–25. Other words that entered Englishat around the same time include: anesthesia, blackleg, federation, hallmark, screeninganti- is a prefix meaning “against,” “opposite of,” “antiparticle of,” used in the formationof compound words (anticline); used freely in combination with elements of any origin (antibody; antifreeze; antiknock; antilepton)