the introduction into a chemical compound of an acyl group
Examples of 'acylation' in a sentence
acylation
These results clearly show that heparin binding accelerates deacylation and slows down acylation.
Gabriel L. C. Nunes, Alyne Simões, Fábio H. Dyszy, Claudio S. Shida, Maria A. Juliano,Luiz Juliano, Tarsis F. Gesteira, Helena B. Nader, Gillian Murphy, Alain F. Chaffotte,Michel E. Goldberg, Ivarne L. S. Tersariol, Paulo C. Almeida 2011, 'Mechanism of Heparin Acceleration of Tissue Inhibitor of Metalloproteases-1 (TIMP-1)Degradation by the Human Neutrophil Elastase', PLoS ONE10.1371/journal.pone.0021525. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The concentrations of acids used for acylation and succinylation were 2,44.
Rini Hustiany,, Dedi Fardiaz2), Anton Apriyantono2), Nuri Andarwulan2) 2005, 'MODIFIKASI ASILASI DAN SUKSINIL PATI TAPIOKA [Modification of Acylation and Succinylationof Tapioca Starch]', Jurnal Teknologi dan Industri Panganhttp://journal.ipb.ac.id/index.php/jtip/article/view/503. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Protein acylation may modify enzyme activity, typically inhibiting it.
Shin Yee Hong, Li Theng Ng, Li Fang Ng, Takao Inoue, Nicholas S Tolwinski, Thilo Hagen,Jan Gruber 2016, 'The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing.', PLoS ONEhttp://europepmc.org/articles/PMC5199114?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These compounds form a covalent adduct with the catalytic serine via an initial acylation step.
Focco van den Akker, Robert A. Bonomo, Robert A. Bonomo, Robert A. Bonomo, RobertA. Bonomo 2018, 'Exploring Additional Dimensions of Complexity in Inhibitor Design for Serine β-Lactamases:Mechanistic and Intra- and Inter-molecular Chemistry Approaches', Frontiers in Microbiologyhttp://journal.frontiersin.org/article/10.3389/fmicb.2018.00622/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The obtained enzymatic preparates were efficient biocatalysts in the acylation reaction of racemic secondary alcohols.
Cristina Paul, Paula Borza, Anca Marcu, Gerlinde Rusu, Mihaela Bîrdeanu, Simona MarcZarcula, Francisc Péter 2016, 'Influence of the Physico-chemical Characteristics of the Hybrid Matrix on the CatalyticProperties of Sol-gel Entrapped Pseudomonas fluorescens Lipase', Nanomaterials and Nanotechnologyhttp://www.intechopen.com/journals/nanomaterials_and_nanotechnology/influence-of-the-physico-chemical-characteristics-of-the-hybrid-matrix-on-the-catalytic-properties-o. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Acylation has furthermore been shown to increase interactions with the lipid membranes of mammalian cells.
Sofie Trier, Lars Linderoth, Simon Bjerregaard, Thomas Lars Andresen, Ulrik Lytt Rahbek 2014, 'Acylation of Glucagon-like peptide-2: interaction with lipid membranes and in vitrointestinal permeability.', PLoS ONEhttp://europepmc.org/articles/PMC4190408?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Acyloxy-derivatives 5 of compounds 4 were obtained by acylation with acid chlorides or acid anhydrides.
D. Rasala, J. Chovancova, P. Kois, J. Lac, E. Solcanyova, A. Puchala, M. Lacova 2005, '3-Formylchromones IV. The Rearrangement of 3-Formylchromone Enamines as a Simple,Facile Route to Novel Pyrazolo[3,4-b]pyridines and the Synthetic Utility of the Latter',Moleculeshttp://www.mdpi.com/1420-3049/10/7/809/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Thus, hydrophilic anthocyanin molecules can be formed and stabilized by glycosylation and acylation.
Nobuhiro Sasaki, Yuzo Nishizaki, Yoshihiro Ozeki, Taira Miyahara 2014, 'The Role of Acyl-Glucose in Anthocyanin Modifications', Moleculeshttp://www.mdpi.com/1420-3049/19/11/18747. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The bagasse acetate butyrates showed increased thermal stability after acylation.
Di Chen,, Ai-Ping Zhang,, Chuan-Fu Liu,, Run-Cang Sun 2012, 'MODIFICATION OF SUGARCANE BAGASSE WITH ACETIC ANHYDRIDE AND BUTYRIC ANHYDRIDE IN IONICLIQUID 1-BUTYL-3-METHYLIMIDAZOLIUM CHLORIDE', BioResourceshttp://ojs.cnr.ncsu.edu/index.php/BioRes/article/view/BioRes_07_3_3476_Chen_ZLS_Sugarcane_Bagasse_Acetic_Anhydride/1611. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Synthesis of these compounds was achieved by two alternative acylation steps followed by ammonolysis.
A. K. Elziaty, G. Bassioni, A. M. A. Hassan, H. A. Derbala, M. S. Abdel-Aziz 2016, 'A Synthetic Approach to Pyrazolopyranopyrimidinones and Pyrazolopyranooxazinones asAntimicrobial Agents', Journal of Chemistryhttp://dx.doi.org/10.1155/2016/5286462. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)