family name Stuart. 1542–87, queen of Scotland (1542–67); daughter of James V of Scotland and Mary of Guise. She was married to Francis II of France (1558–60), her cousin Lord Darnley (1565–67), and the Earl of Bothwell (1567–71), who was commonly regarded as Darnley's murderer. She was forced to abdicate in favour of her son (later James VI of Scotland) and fled to England. Imprisoned by Elizabeth I until 1587, she was beheaded for plotting against the English crown