a semisynthetic penicillin used to treat staphylococcal infections due to penicillin-resistant organisms
cloxacillin in American English
(ˌklɑksəˈsɪlɪn)
noun
Pharmacology
a semisynthetic penicillin, C19H17ClN3NaO5S, used chiefly against penicillin-resistant staphylococcal infections
Word origin
[1965–70; b. chlor-2 and oxacillin]This word is first recorded in the period 1965–70. Other words that entered Englishat around the same time include: Finlandization, genetic engineering, hired gun, red-eye, wraparound
Examples of 'cloxacillin' in a sentence
cloxacillin
Intravenously administered cloxacillin 3 g 6 hourly was started.
J. A. A. S. Jayaweera, W. P. H. Abeydeera, G. R. Ranasinghe 2018, 'Intravenously administered cloxacillin-induced neutropenia with eosinophilia in apatient with infective endocarditis: a case report', Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-018-1933-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Prolonged use of cloxacillin may lead to neutropenia.
J. A. A. S. Jayaweera, W. P. H. Abeydeera, G. R. Ranasinghe 2018, 'Intravenously administered cloxacillin-induced neutropenia with eosinophilia in apatient with infective endocarditis: a case report', Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-018-1933-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Following day 24 of intravenously administered cloxacillin, our patient developed high spike fever.
J. A. A. S. Jayaweera, W. P. H. Abeydeera, G. R. Ranasinghe 2018, 'Intravenously administered cloxacillin-induced neutropenia with eosinophilia in apatient with infective endocarditis: a case report', Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-018-1933-3. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Gram positive isolates were resistant to ampicillin, ciprofloxacin, cotrimoxazole, erythromycin, and cloxacillin.
Basista Prasad Rijal, Deepa Satyal, Narayan Prasad Parajuli 2017, 'High Burden of Antimicrobial Resistance among Bacteria Causing Pyogenic Wound Infectionsat a Tertiary Care Hospital in Kathmandu, Nepal', Journal of Pathogenshttp://dx.doi.org/10.1155/2017/9458218. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Herein we present a case of cloxacillin-induced esophagitis.
Petros Zezos, Ziv Harel, Fred Saibil 2016, 'Cloxacillin: A New Cause of Pill-Induced Esophagitis', Canadian Journal of Gastroenterology and Hepatologyhttp://dx.doi.org/10.1155/2016/2904256. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
There was high resistance to ampicillin and cloxacillin.
Mhada Tumaini V, Fredrick Francis, Matee Mecky I, Massawe Augustine 2012, 'Neonatal sepsis at Muhimbili National Hospital, Dar es Salaam, Tanzania; aetiology,antimicrobial sensitivity pattern and clinical outcome', BMC Public Healthhttp://www.biomedcentral.com/1471-2458/12/904. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Unfortunately, cloxacillin resistance was high among gram-positive organisms.
Abdul Halim Abdul Gafor, Pau Cheong Ping, Anis Farahanum Zainal Abidin, Muhammad ZulhilmieSaruddin, Ng Kah Yan, Siti Qania'ah Adam, Ramliza Ramli, Anita Sulong, Petrick Periyasamy 2014, 'Antibiogram for Haemodialysis Catheter-Related Bloodstream Infections', International Journal of Nephrologyhttp://dx.doi.org/10.1155/2014/629459. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Both of them were resistant to cefaclor, cloxacillin and lincomycin (100%).
Kemal METİNER, Özden BÜYÜKBABA BORAL, Baran ÇELİK, Belgi DİREN SIĞIRCI, Beren BAŞARANKAHRAMAN, Seyyal AK 2016, 'Antimicrobial Resistance Profiles of the Two Porcine Salmonella Typhimurium Isolates',İstanbul Üniversitesi Veteriner Fakültesi Dergisihttp://www.journals.istanbul.edu.tr/iuvfd/article/view/5000192853/5000167992. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Two pin tract infections noted which responded to oral cloxacillin for 5 days.
HK Gupta, KD Khare, D Chaurasia 2012, 'Results of lateral pin fixation for the displaced supracondylar fracture of humerusin children', Journal of College of Medical Sciences-Nepalhttp://nepjol.info/index.php/JCMSN/article/view/6820. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)