a ganglion-blocking drug administered orally to lower high blood pressure. Formula: C11H21N
Word origin
C20: from me(thyl) + cam(phane) (a former name of bornane) + -yl + amine
Examples of 'mecamylamine' in a sentence
mecamylamine
Mecamylamine-precipitated withdrawal symptoms were assessed on day 14.
Alexis Bailey, H Keyworth, James Lind, Andria Tzaikouri, Andre Veloso Rueda, YingChen, Ian Kitchen, Rosana Camarini, Mark Cropley 2018, 'Running away from addiction: Exercise, smoking cessation and neuroscience', Tobacco Prevention and Cessationhttp://www.journalssystem.com/tpc/Running-away-from-addiction-Exercise-smoking-cessation-and-neuroscience,91599,0,2.html. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Mecamylamine alone also caused hyperpolarisations, while atropine alone caused depolarisations and increased firing.
Rasha eElghaba, Nicolas eVautrelle, Enrico eBracci 2016, 'Mutual control of cholinergic and low-threshold spike interneurons in the striatum',Frontiers in Cellular Neurosciencehttp://journal.frontiersin.org/Journal/10.3389/fncel.2016.00111/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In the genes significantly regulated by nicotine but blocked by mecamylamine, 13 enriched pathways were detected.
Ju eWang, Wen Yan Cui, Wen Yan Cui, Jinxue eWei, Dongxiao eSun, Ramana eGutala, JuneGu, Ming D Li 2011, 'Genome-wide expression analysis reveals diverse effects of acute nicotine exposureon neuronal function-related genes and pathways', Frontiers in Psychiatryhttp://journal.frontiersin.org/Journal/10.3389/fpsyt.2011.00005/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)