any one of a group of substances, including factor VIII, the presence of which in the blood is essential for blood clotting to occur
Also called: coagulation factor
Examples of 'coagulation factor' in a sentence
coagulation factor
The activity of coagulation factor was checked daily as necessary.
Dušan Andoljšek, Irena Preložnik Zupan 2012, 'Surgery in adults with congenital coagulation deficiencies: how do we do it?', Zdravniški Vestnikhttp://vestnik.szd.si/index.php/ZdravVest/article/view/749. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Coagulation factor ablation did not affect tumor transduction.
Anniina Koski, Eerika Karli, Anja Kipar, Sophie Escutenaire, Anna Kanerva, AkseliHemminki 2013, 'Mutation of the fiber shaft heparan sulphate binding site of a 5/3 chimeric adenovirusreduces liver tropism.', PLoS ONEhttp://europepmc.org/articles/PMC3621953?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Patients with hemophilia need life-long substituted therapy with deficient coagulation factor.
Tsymbalyuk-Voloshyn I.P. 2016, 'Hemophilia in children: diagnostic and treatment problems', Sovremennaâ Pediatriâhttps://med-expert.com.ua/en/hemophilia-in-children-diagnostic-and-treatment-problems/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, laser treatment did not alter the structure of a model coagulation factor, fibrinogen.
Shaw-Wei D Tsen, David H Kingsley, Karen Kibler, Bert Jacobs, Sara Sizemore, SaraM Vaiana, Jeanne Anderson, Kong-Thon Tsen, Samuel Achilefu 2014, 'Pathogen reduction in human plasma using an ultrashort pulsed laser.', PLoS ONEhttp://europepmc.org/articles/PMC4221090?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This construct was studied with or without additional coagulation factor ablation.
Anniina Koski, Eerika Karli, Anja Kipar, Sophie Escutenaire, Anna Kanerva, AkseliHemminki 2013, 'Mutation of the Fiber Shaft Heparan Sulphate Binding Site of a 5/3 Chimeric AdenovirusReduces Liver Tropism', PLoS ONE10.1371/journal.pone.0060032. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
She was transfused with fresh frozen plasma, blood coagulation factor, and fibrinogen.
Ai-Wu Shi, Xiao-Feng Shen, Hong-Juan Ding, Yao-Qiu Liu, Li Meng, Bill Kalionis 2018, 'Pancreatic carcinoma underlying a complex presentation in late pregnancy: a case report',Journal of Medical Case Reportshttp://link.springer.com/article/10.1186/s13256-018-1911-9. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Impaired coagulation factor synthesis in cirrhosis causes a reduction of most pro- and anticoagulant factors.
Romy M. W. Kremers, Marie-Claire Kleinegris, Marisa Ninivaggi, Bas de Laat, Hugo tenCate, Ger H. Koek, Rob J. Wagenvoord, H. Coenraad Hemker 2017, 'Decreased prothrombin conversion and reduced thrombin inactivation explain rebalancedthrombin generation in liver cirrhosis', PLOS ONE10.1371/journal.pone.0177020. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Interest in the pathogenesis has mostly been focused on the blood coagulation factor.
Pei-Pei Chen, Yu-Chih Lin, Jeng-Hsien Yen, Tsan-Teng Ou, Chen-Ching Wu, Hong-Wen Liu,Wen-Chan Tsai 2006, 'Activation of Endothelial Cells by Antiphospholipid Antibodies—A Possible MechanismTriggering Thrombosis in Patients with Antiphospholipid Syndrome', Kaohsiung Journal of Medical Scienceshttp://www.sciencedirect.com/science/article/pii/S1607551X09703420. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
There are many pieces of evidence of decay among coagulation factor genes.
Shirin Shahbazi 2016, 'Nonsense-mediated mRNA decay among coagulation factor genes', Iranian Journal of Basic Medical Scienceshttp://ijbms.mums.ac.ir/article_6804_a90d929cf0e0d12422231471e851603c.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Clotting insufficiency mostly occurs due to genetically inherited coagulation factor deficiencies such as hemophilia.
Shirin Shahbazi 2016, 'Nonsense-mediated mRNA decay among coagulation factor genes', Iranian Journal of Basic Medical Scienceshttp://ijbms.mums.ac.ir/article_6804_a90d929cf0e0d12422231471e851603c.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)