the bacterium that causes cerebrospinal meningitis
Examples of 'meningococci' in a sentence
meningococci
None of the sera exhibited bactericidal activity against iron-induced wild-type meningococci.
Fadil A Bidmos, Hannah Chan, Uta Praekelt, Isfahan Tauseef, Youssif M Ali, EdwardB Kaczmarski, Ian Feavers, Christopher D Bayliss 2015, 'Investigation into the Antigenic Properties and Contributions to Growth in Blood ofthe Meningococcal Haemoglobin Receptors, HpuAB and HmbR.', PLoS ONEhttp://europepmc.org/articles/PMC4514712?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This interaction leads to cytoskeletal rearrangement and uptake of meningococci.
Heiko Slanina, Sabrina Hebling, Christoph R Hauck, Alexandra Schubert-Unkmeir 2012, 'Cell invasion by Neisseria meningitidis requires a functional interplay between thefocal adhesion kinase, Src and cortactin.', PLoS ONEhttp://europepmc.org/articles/PMC3387252?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Meningococci remodel the plasma membrane of host cells during infection.
Arthur Charles-Orszag, Feng-Ching Tsai, Daria Bonazzi, Valeria Manriquez, Martin Sachse,Adeline Mallet, Audrey Salles, Keira Melican, Ralitza Staneva, Aurélie Bertin, CorinneMillien, Sylvie Goussard, Pierre Lafaye, Spencer Shorte, Matthieu Piel, Jacomine Krijnse-Locker,Françoise Brochard-Wyart, Patricia Bassereau, Guillaume Duménil 2018, 'Adhesion to nanofibers drives cell membrane remodeling through one-dimensional wetting',Nature Communicationshttp://link.springer.com/article/10.1038/s41467-018-06948-x. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Blood grown meningococci are under stress and undergo a metabolic adaptation and energy conservation strategy.
Åsa K Hedman, Ming-Shi Li, Paul R Langford, J Simon Kroll 2012, 'Transcriptional profiling of serogroup B Neisseria meningitidis growing in human blood:an approach to vaccine antigen discovery.', PLoS ONEhttp://europepmc.org/articles/PMC3382141?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A low education level was associated with higher risk of meningococci carriage.
Marco Aurelio Palazzi Sáfadi, Telma Regina Marques Pinto Carvalhanas, Ana Paula deLemos, Maria Cecilia Outeiro Gorla, Maristela Salgado, Lucila O. Fukasawa, Maria GiseleGonçalves, Fabio Higa, Maria Cristina Cunto Brandileone, Claudio Tavares Sacchi, AnaFreitas Ribeiro, Helena Keico Sato, Lucia Ferro Bricks, José Cassio de Moraes 2014, 'Carriage Rate and Effects of Vaccination after Outbreaks of Serogroup C MeningococcalDisease, Brazil, 2010', Emerging Infectious Diseaseshttps://wwwnc.cdc.gov/eid/article/20/5/13-0948_article. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Sixty (7.9%) carried meningococci; risk for carriage was higher in those >14 years of age.
Patricia E. Fitzpatrick, Roland L. Salmon, Paul R. Hunter, Richard J Roberts, StephenR. Palmer 2000, 'Risk Factors for Carriage of Neisseria meningitidis during an Outbreak in Wales',Emerging Infectious Diseaseshttps://wwwnc.cdc.gov/eid/article/6/1/00-0112_article. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Meningococci can cause clusters of disease.
Johannes Elias, Dag Harmsen, Heike Claus, Wiebke Hellenbrand, Matthias Frosch, UlrichVogel 2006, 'Spatiotemporal Analysis of Invasive Meningococcal Disease, Germany', Emerging Infectious Diseaseshttps://wwwnc.cdc.gov/eid/article/12/11/06-0682_article. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, regulatory transcription factors and two-component systems in meningococci involved in adaptation to local nutrient variations are limited.
Yvonne Pannekoek, Robert A. G. Huis in ‘t Veld, Kim Schipper, Sandra Bovenkerk, GertjanKramer, Matthijs C. Brouwer, Diederik van de Beek, Dave Speijer, Arie van der Ende,Julian Parkhill 2017, 'Neisseria meningitidis Uses Sibling Small Regulatory RNAs To Switch from Catapleroticto Anaplerotic Metabolism', mBiohttp://mbio.asm.org/cgi/content/full/8/2/e02293-16. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
After initial adhesion to host cells meningococci form aggregates, through pilus-pilus interactions, termed microcolonies from which the bacteria laterdetach.
Sara Sigurlásdóttir, Jakob Engman, Olaspers Sara Eriksson, Sunil D Saroj, NadezdaZguna, Pilar Lloris-Garcerá, Leopold L Ilag, Ann-Beth Jonsson 2017, 'Host cell-derived lactate functions as an effector molecule in Neisseria meningitidismicrocolony dispersal.', PLoS Pathogenshttp://europepmc.org/articles/PMC5383330?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
During 1999 to 2000, the percentage of meningococci reached 17%, a proportion never reported since recordkeeping began in 1984.
Marie-Christine Fonkoua, Muhamed-Kheir Taha, Pierre Nicolas, Patrick Cunin, Jean-MichelAlonso, Raymond Bercion, Jeanne Musi, Paul M.V. Martin 2002, 'Recent Increase in Meningitis Caused by Neisseria meningitidis Serogroups A and W135,Yaoundé, Cameroon', Emerging Infectious Diseaseshttps://wwwnc.cdc.gov/eid/article/8/3/01-0308_article. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)