a very fine needle that is used in the performance of delicate procedures, esp biological ones
Examples of 'microneedle' in a sentence
microneedle
The last part of this review discusses concerns and challenges regarding microneedle use.
Kevin Ita 2015, 'Transdermal Delivery of Drugs with Microneedles—Potential and Challenges', Pharmaceuticshttp://www.mdpi.com/1999-4923/7/3/90. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
To address these challenges, a commercially available motorized microneedle array skin delivery device was evaluated.
Robyn P Hickerson, Winston C Wey, David L Rimm, Tycho Speaker, Susie Suh, Manuel AFlores, Emilio Gonzalez-Gonzalez, Devin Leake, Christopher H Contag, Roger L Kaspar 2013, 'Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized MicroneedleArray Device', Molecular Therapy: Nucleic Acidshttp://www.sciencedirect.com/science/article/pii/S2162253116301871. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In the clinical test, the microneedle patch was well tolerated by the patient.
David C. Yeo, Elizabeth R. Balmayor, Jan-Thorsten Schantz, Chenjie Xu 2017, 'Microneedle physical contact as a therapeutic for abnormal scars', European Journal of Medical Researchhttp://link.springer.com/article/10.1186/s40001-017-0269-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
After 12-h treatment with the microneedle patch, the non-viable proportion increased to 83.8 ± 11.96%.
David C. Yeo, Elizabeth R. Balmayor, Jan-Thorsten Schantz, Chenjie Xu 2017, 'Microneedle physical contact as a therapeutic for abnormal scars', European Journal of Medical Researchhttp://link.springer.com/article/10.1186/s40001-017-0269-6. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This follows from recent governmental concerns over the use of microneedle systems in dermabrasion.
Alexander Martin, Aaron McConville, Ashleigh Anderson, Anna McLister, James Davis 2017, 'Microneedle Manufacture: Assessing Hazards and Control Measures', Safetyhttps://www.mdpi.com/2313-576X/3/4/25. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The combination of iontophoresis and microneedle application produced higher flux than single application.
Gyubin Noh, Taekwang Keum, Jo-Eun Seo, Santosh Bashyal, Nyeon-Sik Eum, Min Jung Kweon,Sooyeun Lee, Dong Hwan Sohn, Sangkil Lee 2018, 'Iontophoretic Transdermal Delivery of Human Growth Hormone (hGH) and the CombinationEffect of a New Type Microneedle, Tappy Tok Tok®', Pharmaceuticshttp://www.mdpi.com/1999-4923/10/3/153. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Therefore, the microneedle array can potentially be used in many technology applications.
Po Chun Chen, Sheng Jen Hsieh, Chien Chon Chen, Jun Zou 2013, 'A Three-Dimensional Enormous Surface Area Aluminum Microneedle Array with NanoporousStructure', Journal of Nanomaterialshttp://dx.doi.org/10.1155/2013/164953. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Micro-milling was adopted as an environmental-friendly and cost-effective way to fabricate primary metal microneedle masters.
Min Jung Kim, Seok Chan Park, Binod Rizal, Giselle Guanes, Seung-Ki Baek, Jung-HwanPark, Amy R. Betz, Seong-O Choi 2018, 'Fabrication of Circular Obelisk-Type Multilayer Microneedles Using Micro-Milling andSpray Deposition', Frontiers in Bioengineering and Biotechnologyhttp://journal.frontiersin.org/article/10.3389/fbioe.2018.00054/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We describe, for the first time, hydrogel-forming microneedle arrays prepared from "super swelling" polymeric compositions.
Ryan F Donnelly, Maelíosa T C McCrudden, Ahlam Zaid Alkilani, Eneko Larrañeta, EmmaMcAlister, Aaron J Courtenay, Mary-Carmel Kearney, Thakur Raghu Raj Singh, Helen OMcCarthy, Victoria L Kett, Ester Caffarel-Salvador, Sharifa Al-Zahrani, A David Woolfson 2014, 'Hydrogel-forming microneedles prepared from "super swelling" polymers combined withlyophilised wafers for transdermal drug delivery.', PLoS ONEhttp://europepmc.org/articles/PMC4216095?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)