an antiviral drug used in the treatment of AIDS; , AZT
Examples of 'zidovudine' in a sentence
zidovudine
Clinical benefit has been reported with zidovudine and with lamivudine in observational studies.
Rudge Peter, Babiker Abdel, Nose Hirohisa, Mosley Angelina, Barfield Anna, Green Hannah,Furukawa Yoshitaka, Goon Peter, Taylor Graham P, Usuku Koichiro, Osame Mitsuhiro,Bangham Charles RM, Weber Jonathan N 2006, 'Zidovudine plus lamivudine in Human T-Lymphotropic Virus type-I-associated myelopathy:a randomised trial', Retrovirologyhttp://www.retrovirology.com/content/3/1/63. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The cumulative incidence of zidovudine-induced anemia was 37.1% over 2 years.
Anita Shet, Jimmy Antony, Karthika Arumugam, Sunil Kumar Dodderi, Rashmi Rodrigues,Ayesha DeCosta 2014, 'Influence of adverse drug reactions on treatment success: prospective cohort analysisof HIV-infected individuals initiating first-line antiretroviral therapy in India.',PLoS ONEhttp://europepmc.org/articles/PMC3948746?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Consistently higher lipid concentrations were seen with efavirenz compared with atazanavir/r or zidovudine/abacavir.
Janine M Trevillyan, Gerard Wong, Rebekah Puls, Kathy Petoumenos, Sean Emery, NatalieA Mellett, Piyushkumar A Mundra, Peter J Meikle, Jennifer F Hoy 2018, 'Changes in plasma lipidome following initiation of antiretroviral therapy.', PLoS ONEhttp://europepmc.org/articles/PMC6114786?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Combination of lamivudine and zidovudine showed no synergistic antiviral activity.
Yu Cong, Julie Dyall, Brit J. Hart, Lisa Evans DeWald, Joshua C. Johnson, Elena Postnikova,Huanying Zhou, Robin Gross, Oscar Rojas, Isis Alexander, Nicole Josleyn, Tengfei Zhang,Julia Michelotti, Krisztina Janosko, Pamela J. Glass, Mike Flint, Laura K. McMullan,Christina F. Spiropoulou, Tim Mierzwa, Rajarshi Guha, Paul Shinn, Sam Michael, CarleenKlumpp-Thomas, Crystal McKnight, Craig Thomas, Ann E. Eakin, Kathleen G. O’Loughlin,Carol E. Green, Paul Catz, Jon C. Mirsalis, Anna N. Honko, Gene G. Olinger, RichardS. Bennett, Michael R. Holbrook, Lisa E. Hensley, Peter B. Jahrling 2016, 'Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus', PLOS ONE10.1371/journal.pone.0166318. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These patients were on zidovudine for 1 to 7 years.
Amitabh Sagar, Ambika P Mohanty, Ashish Bahal 2010, 'Zidovudine-induced myopathy: A study in Indian patients', Journal of Neurosciences in Rural Practicehttp://www.ruralneuropractice.com/article.asp?issn=0976-3147;year=2010;volume=1;issue=2;spage=63;epage=66;aulast=Sagar. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
He started antiretroviral therapy with zidovudine, lamivudine, and lopinavir.
Geysa Maria Nogueira Farias, José Reginaldo Pinto, Juliana Carneiro Melo, Lara GurgelFernandes Távora, Danielle Malta Lima, Fernanda Judith Viana Correia, Geraldo Bezerrada Silva Júnior 2018, 'Kyrle's disease associated with HIV infection, diabetes, and chronic kidney disease',Indian Journal of Pathology and Microbiologyhttp://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=3;spage=414;epage=417;aulast=Nogueira. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The most used medications were lamivudine-zidovudine (51.6%), lopinavir-ritonavir (36%) and efavirenz (24.5%).
Jorge E. Machado-Alba, Miguel A. Atehortua-Otero, Diego A. Cortés-Mejía 2018, 'Profile of antiretroviral agents use in Colombia', Biomédica: revista del Instituto Nacional de Saludhttps://www.revistabiomedica.org/index.php/biomedica/article/view/3885. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Zidovudine was determined in plasma and tissues by reverse phase high performance liquid chromatography.
Shah Purvin, Parameswara Rao Vuddanda, Sanjay Kumar Singh, Achint Jain, Sanjay Singh 2014, 'Pharmacokinetic and Tissue Distribution Study of Solid Lipid Nanoparticles of Zidovudinein Rats', Journal of Nanotechnologyhttp://dx.doi.org/10.1155/2014/854018. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)