It was revealed that experimental pancreatitis associated with progressive tissue hypoxia and antioxidant misbalance.
А V Letounovski, Z I Мiкаshinowich 2011, 'Metabolic changes in erythrocytes at experimental alcoholic pancreatitis and theircorrection', RUDN Journal of Medicinehttp://journals.rudn.ru/medicine/article/view/3554. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Replacement into the subclavian vein led to cardio-respiratory misbalance due to severe pleural effusion.
Armin-Johannes Michel, Johannes Brandner, Sebastian Cotofana, Mircia Ardelean, RomanMetzger 2016, 'Infusoabdomen with abdominal compartment in extremely low birth weight neonates',Journal of Pediatric Surgery Case Reportshttp://www.sciencedirect.com/science/article/pii/S2213576615300270. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
A misbalance in prohormone convertase levels may interrupt the normal processing of islet amyloid polypeptide and induce amyloid formation.
Sara Ullsten, Sara Bohman, Marie E Oskarsson, K Peter R Nilsson, Gunilla T Westermark,Per-Ola Carlsson 2017, 'Islet amyloid deposits preferentially in the highly functional and most blood-perfusedislets', Endocrine Connectionshttp://www.endocrineconnections.com/content/6/7/458.full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This phenotype alteration was a consequence of a sphingolipid misbalance with an increase in ceramide levels.
Bruno Jaime Santacreu, Lucila Gisele Pescio, Daniela Judith Romero, Gerardo Raúl Corradi,Norma Sterin-Speziale, Nicolás Octavio Favale 2019, 'Sphingosine kinase and sphingosine-1-phosphate regulate epithelial cell architectureby the modulation of de novo sphingolipid synthesis', PLOS ONE10.1371/journal.pone.0213917. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)