a small molecule that combines with, and activates, a repressor
corepressor in American English
(ˌkourɪˈpresər)
noun
Genetics
a molecule that is capable of combining with a specific repressor molecule and activatingit, thereby blocking gene transcription
Word origin
[1960–65; co- + repressor]This word is first recorded in the period 1960–65. Other words that entered Englishat around the same time include: Pap test, deinstitutionalize, disco, pop art, power playco- is a prefix meaning “with,” “together,” “in association,” sometimes with the derivedsense “auxiliary, subsidiary” (coenzyme; copilot), and, in mathematics and astronomy, with the sense “complement” (codeclination)
Examples of 'corepressor' in a sentence
corepressor
The toxin protein commonly works as a transcriptional corepressor that remodels and stabilizes the antitoxin.
Finbarr Hayes, Barbara Kędzierska 2014, 'Regulating Toxin-Antitoxin Expression: Controlled Detonation of Intracellular MolecularTimebombs', Toxinshttp://www.mdpi.com/2072-6651/6/1/337. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These contexts were shown to play a role in differential corepressor recruitment.
Shira Rockowitz, Wen-Hui Lien, Erika Pedrosa, Gang Wei, Mingyan Lin, Keji Zhao, HerbertM Lachman, Elaine Fuchs, Deyou Zheng 2014, 'Comparison of REST cistromes across human cell types reveals common and context-specificfunctions.', PLoS Computational Biologyhttp://europepmc.org/articles/PMC4055426?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)