a nucleotide or one of several elements that combine to form nucleic acid
Examples of 'mononucleotide' in a sentence
mononucleotide
The most abundant motif was mononucleotide (52.33%), followed by trinucleotide (31.96%), and dinucleotide (14.57%).
Liuyi Yang, Changlong Wen, Hong Zhao, Qianchun Liu, Jingjing Yang, Lecheng Liu, YongqinWang 2015, 'Development of Polymorphic Genic SSR Markers by Transcriptome Sequencing in the WelshOnion (Allium fistulosum L.)', Applied Scienceshttp://www.mdpi.com/2076-3417/5/4/1050. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Microsatellite instability was ruled out by the allelic pattern of two major mononucleotide repeats.
Irminger-Finger Irmgard, Mikou Panagiota, Jefford Charles-Edward, Merk-Loretti Sophie,Chiourea Maria, Papaioannou George, Gagos Sarantis, Liossi Anna, Blouin Jean-Louis,Dahoun Sophie 2008, 'Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomeraseactivity', Molecular Cytogeneticshttp://www.molecularcytogenetics.org/content/1/1/20. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We found that mononucleotide, dinucleotide, and trinucleotide repeat motifs were themost prevalent (95.91%).
Ming-Bao Luan, Ze-Mao Yang, Juan-Juan Zhu, Xin Deng, Chen-Chen Liu, Xiao-Fei Wang,Ying Xu, Zhi-Min Sun, Jian-Hua Chen 2016, 'Identification, evaluation, and application of the genomic-SSR loci in ramie', Acta Societatis Botanicorum Poloniaehttps://pbsociety.org.pl/journals/index.php/asbp/article/view/6486. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Somatic mutations in mononucleotide repeats are commonly used to assess the mismatch repair status of tumours.
Lisa Redford, Ghanim Alhilal, Stephanie Needham, Ottie O'Brien, Julie Coaker, JohnTyson, Leonardo Maldaner Amorim, Iona Middleton, Osagi Izuogu, Mark Arends, Anca Oniscu,Ángel Miguel Alonso, Sira Moreno Laguna, Richard Gallon, Harsh Sheth, Mauro Santibanez-Koref,Michael S. Jackson, John Burn 2018, 'A novel panel of short mononucleotide repeats linked to informative polymorphismsenabling effective high volume low cost discrimination between mismatch repair deficientand proficient tumours', PLOS ONE10.1371/journal.pone.0203052. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We screened the genome sequences of different organisms for an important determinant of stability, the presence of mononucleotide repeats.
Martin Ackermann, Lin Chao 2006, 'DNA sequences shaped by selection for stability.', PLoS Geneticshttp://europepmc.org/articles/PMC1378130?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Finally, the analysis of bryophyte coding sequences showed mononucleotide, dinucleotide and trinucleotide compositional trends resembling those of higher plants.
Andrea Porceddu, Salvatore Camiolo 2011, 'Spatial analyses of mono, di and trinucleotide trends in plant genes.', PLoS ONEhttp://europepmc.org/articles/PMC3148226?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Furthermore, 97.75% of the 267,243 simple sequence repeats identified from these scaffolds were mononucleotide, dinucleotide, and trinucleotide repeats.
Xupo Ding, Wenli Mei, Shengzhuo Huang, Hui Wang, Jiahong Zhu, Wei Hu, Zehong Ding,Weiwei Tie, Shiqing Peng, Haofu Dai 2018, 'Genome survey sequencing for the characterization of genetic background of Dracaenacambodiana and its defense response during dragon's blood formation.', PLoS ONEhttp://europepmc.org/articles/PMC6294377?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In the first case, we found a mononucleotide deletion, and in the second, a mononucleotide insertion.
Maria V. Kuznetsova, Dmitry Yu. Trofimov, Ekaterina S. Shubina, Taisiya O. Kochetkova,Natalia A. Karetnikova, Ilya Yu. Barkov, Vladimir A. Bakharev, Oleg A. Gusev, OlegA. Gusev, Oleg A. Gusev, Gennady T. Sukhikh 2017, 'Two Novel Mutations Associated With Ataxia-Telangiectasia Identified Using an IonAmpliSeq Inherited Disease Panel', Frontiers in Neurologyhttp://journal.frontiersin.org/article/10.3389/fneur.2017.00570/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)