请输入您要查询的英文单词：

　

单词 valinomycin
释义

valinomycin in American English

(ˌvælənoʊˈmaɪsɪn)
noun
an antibiotic polypeptide isolated from soil bacteria, that promotes the movement of potassium ions in cells
Word origin
< valine + -mycin

Examples of 'valinomycin' in a sentence
valinomycin

After 24 h fibroblasts and melanoma cells developed mitochondrial potential changes similar to valinomycin.
Marian Hernández-Colina, Alberto Martín Cermeño, Alexis Díaz García 2016, 'Selective cytotoxic effect of 1-O-undecylglycerol in human melanoma cells', Journal of Pharmacy & Pharmacognosy Researchhttp://jppres.com/jppres/pdf/vol4/jppres16.106_4.2.84.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ionophores such as valinomycin and nigericin are potent tools for studying the impact of ion perturbance on cellular functions.
Michaela Jakubkova, Vladimira Dzugasova, Dominika Truban, Lenka Abelovska, IngridBhatia-Kissova, Martin Valachovic, Vlasta Klobucnikova, Lucia Zeiselova, Peter Griac,Jozef Nosek, Lubomir Tomaska 2016, 'Identification of Yeast Mutants Exhibiting Altered Sensitivity to Valinomycin andNigericin Demonstrate Pleiotropic Effects of Ionophores on Cellular Processes.', PLoS ONEhttp://europepmc.org/articles/PMC5053447?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Loss of autophagosomal protein function leads to valinomycin sensitivity and an overproduction of reactive oxygen species upon mitochondrial damage.
Alba Timón-Gómez, Alba Timón-Gómez, David Sanfeliu-Redondo, Amparo Pascual-Ahuir,Markus Proft 2018, 'Regulation of the Stress-Activated Degradation of Mitochondrial Respiratory Complexesin Yeast', Frontiers in Microbiologyhttp://journal.frontiersin.org/article/10.3389/fmicb.2018.00106/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Further mitochondrial damage by valinomycin treatment of yeast cells triggers the mitophagic removal of the same respiratory complexes.
Alba Timón-Gómez, Alba Timón-Gómez, David Sanfeliu-Redondo, Amparo Pascual-Ahuir,Markus Proft 2018, 'Regulation of the Stress-Activated Degradation of Mitochondrial Respiratory Complexesin Yeast', Frontiers in Microbiologyhttp://journal.frontiersin.org/article/10.3389/fmicb.2018.00106/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The mitochondriotoxic mechanism of triclosan differs from that of valinomycin, cereulide and the enniatins by not involving potassiumionophoric activity.
Charmaine Ajao, Maria A. Andersson, Vera V. Teplova, Szabolcs Nagy, Carl G. Gahmberg,Leif C. Andersson, Maria Hautaniemi, Balazs Kakasi, Merja Roivainen, Mirja Salkinoja-Salonen 2015, 'Mitochondrial toxicity of triclosan on mammalian cells', Toxicology Reportshttp://www.sciencedirect.com/science/article/pii/S221475001500044X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We identified nearly 130 genes whose absence leads either to resistance or to hypersensitivity to valinomycin and/or nigericin.
Michaela Jakubkova, Vladimira Dzugasova, Dominika Truban, Lenka Abelovska, IngridBhatia-Kissova, Martin Valachovic, Vlasta Klobucnikova, Lucia Zeiselova, Peter Griac,Jozef Nosek, Lubomir Tomaska 2016, 'Identification of Yeast Mutants Exhibiting Altered Sensitivity to Valinomycin andNigericin Demonstrate Pleiotropic Effects of Ionophores on Cellular Processes', PLOS ONE10.1371/journal.pone.0164175. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The use of cereulide standard was also compared to the most frequently used surrogate standard, the antibiotic valinomycin.
Aida Zuberovic Muratovic, Rikard Tröger, Kristina Granelli, Karl-Erik Hellenäs 2014, 'Quantitative Analysis of Cereulide Toxin from Bacillus cereus in Rice and Pasta UsingSynthetic Cereulide Standard and 13C6-Cereulide Standard—A Short Validation Study',Toxinshttp://www.mdpi.com/2072-6651/6/12/3326. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Bioassay-guided isolation and purification yielded three previously known compounds namely, cyclic depsipeptide valinomycin, indolocarbazole alkaloid staurosporine and butenolide.
Heidrun Moll, Ute Hentschel, Chris M. Ireland, Tim S. Bugni, Svitlana Kozytska, SheilaMarie Pimentel-Elardo 2010, 'Anti-Parasitic Compounds from Streptomyces sp. Strains Isolated from MediterraneanSponges', Marine Drugshttp://www.mdpi.com/1660-3397/8/2/373/. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
随便看

　

英语词典包含298861条英英释义在线翻译词条，基本涵盖了全部常用单词的英英翻译及用法，是英语学习的有利工具。

　

Copyright © 2004-2022 Newdu.com All Rights Reserved
更新时间：2024/12/22 14:07:08