单词	myelofibrosis
释义	myelofibrosis noun my·​e·​lo·​fi·​bro·​sis ˌmī-ə-lō-fī-ˈbrō-səs  : an anemic condition in which bone marrow becomes fibrotic and the liver and spleen usually exhibit a development of blood-cell precursors myelofibrotic ˌmī-ə-lō-fī-ˈbrä-tik  adjective Example Sentences Recent Examples on the Web The deal was struck three months after Sierra’s lead drug, a treatment for the blood cancer myelofibrosis, succeeded in a late-stage clinical trial. Adam Feuerstein, STAT, 14 Apr. 2022 Constellation, based in Cambridge, Mass. is in the late stage of clinical trials for a drug to treat patients with myelofibrosis, a type of bone marrow cancer. Adam Feuerstein, STAT, 2 June 2021 The cause was myelofibrosis, a blood disorder, said a son, Robert Wiser. Washington Post, 3 June 2021 With 30 myelofibrosis patients now treated and evaluable in its mid-stage study, the 24-week spleen response rate to CPI-0610 — when used on top of Incyte’s market-leading drug Jakafi — stands at 63%. Adam Feuerstein, STAT, 12 June 2020 The cause was complications of a stem cell transplant in 2013 to treat her myelofibrosis, a chronic form of leukemia, her partner, Steve Clicque, said. New York Times, 21 Apr. 2020 About two years ago, Pamela Dobay received a stem-cell transplant to treat her myelofibrosis, a rare type of bone marrow cancer. Katie Camero, WSJ, 8 Apr. 2020 Fedratinib targets a mutation called JAK2 that drives certain kinds of myelofibrosis. San Diego Union-Tribune, 19 Aug. 2019 The drug, fedratinib, treats certain kinds of a bone marrow cancer called myelofibrosis. San Diego Union-Tribune, 19 Aug. 2019 See More Word History Etymology myelo- + fibrosis First Known Use 1937, in the meaning defined above Medical Definition myelofibrosis noun my·​e·​lo·​fi·​bro·​sis ˌmī-ə-lō-fī-ˈbrō-səs  plural myelofibroses -ˌsēz  : an anemic condition in which bone marrow becomes fibrotic and the liver and spleen usually exhibit a development of blood-cell precursors
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