单词	mercaptopurine
释义	mercaptopurine noun mer·​cap·​to·​pu·​rine (ˌ)mər-ˌkap-tə-ˈpyu̇r-ˌēn  : an antimetabolite C5H4N4S that interferes especially with the metabolism of purine bases and the biosynthesis of nucleic acids and that is sometimes used in the treatment of acute leukemia Example Sentences Recent Examples on the Web The next breakthrough, in 1950, was the development of 6-MP (mercaptopurine) by Gertrude Elion and George Hitchings, who would go on to receive the Nobel Prize. Marie Mccullough, https://www.inquirer.com, 6 June 2019 Using this targeted method, Elion helped develop such drugs as mercaptopurine, which changed childhood leukemia from a death-sentence to a condition that most survive. Ray Cavanaugh, Time, 23 Jan. 2018 Word History Etymology mercaptan + -o- + purine First Known Use circa 1952, in the meaning defined above Medical Definition mercaptopurine noun mer·​cap·​to·​pu·​rine (ˌ)mər-ˌkap-tə-ˈpyu̇(ə)r-ˌēn  : an antimetabolite C5H4N4S that interferes especially with the metabolism of purine bases and the biosynthesis of nucleic acids and that is sometimes useful in the treatment of acute leukemia
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