单词	gene conversion
释义	gene conversion noun : a genetic process that involves nonreciprocal meiotic recombination in heterozygotes in which a mismatched DNA sequence from one heteroduplex DNA strand is replaced with a sequence complementary to the other strand resulting in aberrant gametic ratios (such as 3:1) and that is observed especially in ascomycetous fungi Example Sentences Recent Examples on the Web Their new experiments suggest that embryos borrow DNA templates from themselves to make repairs—a process called gene conversion—up to 40 percent of the time. Megan Molteni, Wired, 29 Oct. 2020 Word History First Known Use 1955, in the meaning defined above Medical Definition gene conversion noun : a genetic process that is sometimes associated with meiotic recombination in heterozygotes if heteroduplex DNA is formed, that involves the selective enzymatic excision of a mismatched DNA sequence from one heteroduplex strand and replacement with a nucleotide sequence complementary to the other strand so that the two DNA strands are genetically identical, and that results in aberrant gametic ratios (as 3:1 or 1:3 instead of 2:2)
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