: a synthetic opiate antagonist C20H23NO4 administered in the form of its hydrochloride
Example Sentences
Recent Examples on the WebThat's where opioid antagonists, like naltrexone and naloxone, come in. Sarah Fielding, Health.com, 19 Nov. 2021 Glaser cites a 2001 study by Sinclair in the journal Alcohol and Alcoholism that shows a 78 percent success rate of naltrexone alone in helping patients cut their drinking down to 10 drinks a week. Virginia Heffernan, Wired, 19 Apr. 2022 The lawsuit filed Thursday addresses the use of methadone, naltrexone and buprenorphine— including the brand name Suboxone— all of which are approved by the federal Food and Drug Administration. Claudia Lauer, ajc, 25 Feb. 2022 Fans of naltrexone as treatment also point to its lack of street value as another advantage over buprenorphine and methadone.Freep.com, 21 Jan. 2022 Methadone is one of three medications approved to treat opioid addiction; the other two are buprenorphine and extended-release naltrexone. Paul J. Joudrey And Adam J. Gordon, STAT, 25 Dec. 2021 Currently, people seeking help with addiction can take medications like naltrexone, methadone and buprenorphine: These often life-changing medications prevent cravings, feelings of being high or both. Tribune News Service, oregonlive, 6 Jan. 2022 Drugs currently on the market that are used to treat opioid use disorder, like naltrexone and buprenorphine, bind to opioid receptors in the brain. Will Yakowicz, Forbes, 7 Dec. 2021 The drugs used in MAT—such as buprenorphine, methadone, or naltrexone—help manage cravings and withdrawal. Laura Hilgers, Health.com, 9 Nov. 2021 See More
Word History
Etymology
N-allyl + trex- (as in methotrexate) + -one
First Known Use
1973, in the meaning defined above
Medical Definition
naltrexone
noun
nal·trex·one nal-ˈtrek-ˌsōn
: a synthetic opiate antagonist administered especially in the form of its hydrochloride C20H23NO4·HCl to maintain a drug-free state in detoxified opiate-dependent patients or to maintain abstinence in alcohol-dependent patients