单词	cholinesterase
释义	cholinesterase noun cho·​lin·​es·​ter·​ase ˌkō-lə-ˈne-stə-ˌrās  -ˌrāz 1 : an enzyme that occurs chiefly at neuromuscular junctions and promotes the hydrolysis of acetylcholine at postsynaptic receptors : acetylcholinesterase 2 : butyrylcholinesterase Example Sentences Recent Examples on the Web Donepezil and others like it, such galantamine and rivastigmine, belong to a class of medications called cholinesterase inhibitors, typically prescribed for mild to moderate Alzheimer's disease. Jacqueline Howard, CNN, 9 June 2021 Carbamates and organophosphates, both pesticides, use cholinesterase inhibitors to neutralize the nervous system of insects. Miriam Berger, Washington Post, 26 Aug. 2020 The nerve agent is a cholinesterase inhibitor, part of the class of substances that doctors at Charite said last week had shown up in Navalny's system. Arkansas Online, 2 Sep. 2020 The nerve agent is a cholinesterase inhibitor, part of the class of substances that doctors at the Charite initially identified in Navalny. Geir Moulson, Anchorage Daily News, 2 Sep. 2020 Still, Loeb notes that cholinesterase inhibitors, which are often used for people with Alzheimer's, can help improve cognition and alertness in patients with Lewy body dementia. Jayme Deerwester, USA TODAY, 2 Sep. 2020 German doctors have confirmed Navalny had symptoms of poisoning, likely by a cholinesterase inhibitor, which includes highly toxic chemical nerve agents and pesticides. Robyn Dixon, Washington Post, 31 Aug. 2020 Doctors in Berlin said he was exposed to a cholinesterase inhibitor, a chemical group that includes some nerve agents, though the exact compound hasn’t yet been identified. Iain Rogers, Bloomberg.com, 29 Aug. 2020 Found in some drugs, pesticides and chemical nerve agents, cholinesterase inhibitors block the breakdown of a key chemical in the body, acetycholine, that transmits signals between nerve cells. Fox News, 28 Aug. 2020 See More Word History First Known Use 1932, in the meaning defined at sense 1 Medical Definition cholinesterase noun cho·​lin·​es·​ter·​ase ˌkō-lə-ˈnes-tə-ˌrās, -ˌrāz  1 : an enzyme that occurs chiefly at neuromuscular junctions and promotes the hydrolysis of acetylcholine at postsynaptic receptors : acetylcholinesterase The acetylcholine released by cholinergic fibers is rapidly decomposed by the action of cholinesterase. John W. Hole, Human Anatomy & Physiology As a cholinesterase inhibitor, it increases parasympathetic nervous system activity. T. A. Farley et al., The Journal of the American Medical Association 2 : butyrylcholinesterase
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