chromatolysis
noun
chro·ma·tol·y·sis ˌkrō-mə-ˈtä-lə-səs 
: the dissolution and breaking up of chromophil material (such as chromatin) of a cell and especially a nerve cell
chromatolytic
krō-ˌma-tə-ˈli-tik
adjective krə-
Word History
Etymology
borrowed from French chromatolyse, from chromato- chromato- + -lyse -lysis
Note: Term introduced by the Romanian neurologist Georges Marinesco (Gheorghe Marinescu, 1863-1938), probably first in "Des polynévrites en rapport avec les lésions secondaires et les lésions primitives des cellules nerveuses," Revue neurologique, tome 4 (1896), p. 133.
First Known Use
1901, in the meaning defined above
Medical Definition
chromatolysis
noun
chro·ma·tol·y·sis ˌkrō-mə-ˈtäl-ə-səs
plural chromatolyses -ˌsēz
: the dispersal of Nissl substance in the cell body of a neuron resulting from axonal stress (as that induced by injury or neurodegenerative disease)
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