: an antipsychotic drug C18H19ClN4 used in the treatment of schizophrenia
Example Sentences
Recent Examples on the WebFor them, clozapine is the gold standard treatment. Brian Barnett, STAT, 9 May 2022 Many medications can cause excess salivation, such as clonozapam (Klonopin) and clozapine (Clozaril). Dr. Keith Roach, oregonlive, 7 Oct. 2021 He was evaluated by a doctor, now a defendant in the lawsuit, who did not prescribe clozapine. Sydney Czyzon, Milwaukee Journal Sentinel, 3 July 2019 Research suggests that chlorpromazine is the most likely to cause seizures among typical antipsychotics while clozapine is most likely among atypicals. Kimberly Truong, SELF, 7 Dec. 2018 Twenty days later, Mathew stopped regularly taking clozapine, an antipsychotic used to treat schizophrenia.oregonlive.com, 22 June 2019 Research suggests that this is more likely to be an issue with typical antipsychotics than atypical ones, such as olanzapine, clozapine, and aripiprazole—with the exception of risperidone. Kimberly Truong, SELF, 7 Dec. 2018 Research suggests that chlorpromazine is the most likely to cause seizures among typical antipsychotics while clozapine is most likely among atypicals. Kimberly Truong, SELF, 7 Dec. 2018 The report thoughtfully takes a strong stance and recommends the wider use of clozapine, an atypical antipsychotic medication that, for people with schizophrenia, is often superior to other medications. D. J. Jaffe, National Review, 18 Dec. 2017 See More
Word History
Etymology
International Scientific Vocabulary chlor- + -zapine, alteration of -azepine (as in benzodiazepine)
First Known Use
1970, in the meaning defined above
Medical Definition
clozapine
noun
clo·za·pine ˈklō-zə-ˌpēn
: an antipsychotic drug C18H19ClN4 with serious side effects (as seizures and agranulocytosis) that is used in the management of schizophrenia
Note: Clozapine is marketed under the trademark Clozaril.