inanition

Inanition describes a state of suffering from either a literal emptiness (of sustenance) or a metaphorical emptiness (of interest or energy), so it should come as no surprise that the word ultimately derives from the same idea in Latin. Inanition, which first appeared in Middle English in the 14th century as in-anisioun, can be traced back to the Latin verb inanire, meaning "to make empty," which in turn comes from inanis (meaning "empty"). Another far more common descendant of inanis is inane. The family resemblance is clear: inane is used describe things lacking significance or substance.