单词	colony-stimulating factor
释义	colony-stimulating factor noun col·​o·​ny-stim·​u·​lat·​ing factor ˈkä-lə-nē-ˈstim-yə-ˈlā-tiŋ  : any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture Example Sentences Recent Examples on the Web Giving mice a drug that blocked the critical protein colony-stimulating factor 1, which microglia need to survive, was shown to remove around 90 percent of microglia in the brain. Jason Ulrich, Scientific American, 1 Aug. 2021 Otilimab is a monoclonal antibody against the granulocyte macrophage colony-stimulating factor, or GM-CSF, which stimulates the production of white blood cells. Matthew Herper, STAT, 27 Feb. 2021 The virus, called T-VEC, produces a substance called granulocyte macrophage colony-stimulating factor. Bradley J. Fikes, sandiegouniontribune.com, 7 Sep. 2017 Word History First Known Use 1967, in the meaning defined above Medical Definition colony-stimulating factor noun col·​o·​ny-stim·​u·​lat·​ing factor -ˌstim-yə-ˌlāt-iŋ-  : any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture see granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, interleukin-3, macrophage colony-stimulating factor
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