单词 | major histocompatibility complex |
释义 | major histocompatibility complexnoun plural major histocompatibility complexes : a group of genes in mammals that code for cell-surface polymorphic glycoprotein molecules which display antigenic peptide fragments for T cell recognition and aid in the ability of the immune system to determine self from nonself Note: The genes of the major histocompatibility complex and the molecules they determine are grouped into 2 classes. Glycoprotein molecules of class I are expressed on all nucleated cells and are recognized by CD8 on the surface of cytotoxic T cells. Glycoprotein molecules of class II are restricted to antigen-presenting cells and are recognized by CD4 on the surface of helper T cells. major histocompatibility complex molecules —abbreviation MHC compare HLA |
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