英语词汇“Cooley's anemia”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典

Medical Definition

Cooley's anemia

noun

Coo·ley's anemia ˌkü-lēz- How to pronounce Cooley's anemia (audio)

variants also Cooley's disease

: an inherited disorder of hemoglobin synthesis that is the most severe form of beta-thalassemia, is marked by severe anemia associated with deficient hemoglobin, the presence of microcytes, and accelerated red cell destruction, and is associated with enlargement of the liver and spleen, an increase in the erythroid bone marrow, bone deformities, and poor growth rate

called also beta-thalassemia major, thalassemia major

Note: Cooley's anemia is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene located on the chromosome numbered 11. Cooley's anemia occurs especially in individuals of Mediterranean ancestry and necessitates regular blood transfusions throughout life.

单词	Cooley's anemia
释义	Cooley's anemia noun Coo·ley's anemia ˈkü-lēz- : an inherited disorder of hemoglobin synthesis that is the most severe form of beta-thalassemia, is marked by severe anemia associated with deficient hemoglobin, the presence of microcytes, and accelerated red cell destruction, and is associated with enlargement of the liver and spleen, an increase in erythroid bone marrow, bone deformities, and poor growth rate Note: Cooley's anemia is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene located on the chromosome numbered 11. Cooley's anemia occurs especially in individuals of Mediterranean ancestry and necessitates regular blood transfusions throughout life. Word History Etymology Thomas B. Cooley †1945 American pediatrician First Known Use 1934, in the meaning defined above Medical Definition Cooley's anemia noun Coo·ley's anemia ˌkü-lēz- variants also Cooley's disease : an inherited disorder of hemoglobin synthesis that is the most severe form of beta-thalassemia, is marked by severe anemia associated with deficient hemoglobin, the presence of microcytes, and accelerated red cell destruction, and is associated with enlargement of the liver and spleen, an increase in the erythroid bone marrow, bone deformities, and poor growth rate called also beta-thalassemia major, thalassemia major Note: Cooley's anemia is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene located on the chromosome numbered 11. Cooley's anemia occurs especially in individuals of Mediterranean ancestry and necessitates regular blood transfusions throughout life.
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Cooley's anemia

noun

Word History

Medical Definition

noun