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单词 cooperativity
释义

cooperativity

noun

co·​op·​er·​a·​tiv·​i·​ty kō-ˌä-p(ə-)rə-ˈti-və-tē How to pronounce cooperativity (audio)
plural cooperativities
: the quality or state of being cooperative
To safeguard the scientific enterprise, cooperativity and humility need to instead become central virtues of science. Natalie Koffler
"It wasn't such a huge amount to achieve this cooperativity between these two different species" because wolves and humans shared similar social structures, [John] Allman argued. Minerva Canto
specifically, biochemistry : the molecular interaction between a ligand and a macromolecule (such as a protein) having two or more binding sites in which binding of a ligand to one site positively or negatively influences subsequent ligand binding at other sites by either increasing or decreasing the affinity of other binding sites for a ligand
Cooperativity refers to the characteristic that the remaining hemoglobin chains will have greater affinity for O2 after one of the subunits has already bound O2. Shannon Haymond et al.
… a reduction in receptor affinity for its ligand with increasing saturation of binding sites (so-called 'negative cooperativity') has been described for a number of hormones … Martin Raff

Word History

First Known Use

1965, in the meaning defined above

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更新时间:2024/12/23 13:57:02