imipenem
noun
im·i·pen·em ˌi-mə-ˈpe-nəm 
: a semisynthetic carbapenem antibiotic C12H17N3O4S·H2O that is derived from a bacterium (Streptomyces cattleya) and is effective against gram-negative and gram-positive bacteria
Word History
First Known Use
1983, in the meaning defined above
Medical Definition
imipenem
noun
im·i·pen·em ˌim-ə-ˈpen-əm
: a semisynthetic beta-lactam C12H17N3O4S·H2O that is derived from an antibiotic produced by a bacterium of the genus Streptomyces (S. cattleya) and is effective against gram-negative and gram-positive bacteria
Note: Because imipenem is hydrolyzed by a dipeptidase in the kidney, it is administered with cilastatin, an inhibitor of this enzyme.
Five days before admission, the patient was evaluated by an infectious-disease specialist and readmitted to the other hospital for intravenous administration of a three-day course of imipenem-cilastatin …
Stephen I. Pelton et al., The New England Journal of Medicine
Stephen I. Pelton et al., The New England Journal of Medicine