单词	cross-resistance
释义	cross-resistance noun cross-re·​sis·​tance ˌkrȯs-ri-ˈzi-stən(t)s  : tolerance (as of a bacterium) to a usually toxic substance (such as an antibiotic) that is acquired not as a result of direct exposure but by exposure to a related substance Word History First Known Use 1946, in the meaning defined above Medical Definition cross-resistance noun cross-re·​sis·​tance ˌkrȯs-ri-ˈzis-tən(t)s  : tolerance (as of a bacteria, malignant cell, or insect) to a usually toxic substance (as an antibiotic, chemotherapy drug, or pesticide) that is acquired not as a result of direct exposure but by exposure to a related substance The history of drug resistance in falciparum malaria suggests that these compounds may also enjoy only a short-lived glory and that cross-resistance with related compounds can be expected. David J. Wyler, The Journal of the American Medical Association … paclitaxel and docetaxel are being incorporated into adjuvant regimens on the basis of their antitumor activity in advanced breast cancer and the absence of cross-resistance with doxorubicin. Charles L. Shapiro, et al., The New England Journal of Medicine
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