sildenafil

noun

sil·den·a·fil sil-ˈde-nə-ˌfil How to pronounce sildenafil (audio)

: a drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection

Note: Sildenafil is marketed under the trademarks Revatio and Viagra.

Example Sentences

Recent Examples on the Web The most common drugs, such as sildenafil (Viagra), work mostly on blood vessels but also have effects on raising both testosterone levels and estrogen levels in men.

Dr. Keith Roach, oregonlive, 15 Apr. 2022 Doctors have indeed been using sildenafil in some cases to treat PAH.

Bruce Y. Lee, Forbes, 18 Apr. 2022 The interaction between nitrates and sildenafil can lower blood pressure to dangerous levels, the FDA warns.

Chris Smith, BGR, 7 Mar. 2022 The capsules were tested and found to contain sildenafil, the active ingredient in Viagra and other prescription medications used to treat erectile dysfunction in men.

Elainie Barraza, orlandosentinel.com, 1 Feb. 2022 According to a new study, patients who took sildenafil, most commonly known as the drug Viagra, were less likely to suffer from Alzheimer’s disease.

Joshua Hawkins, BGR, 8 Dec. 2021 Feixiong Cheng, a senior author on the study, says that the use of sildenafil helped reduce the likelihood of Alzheimer’s in individuals with coronary artery disease, hypertension, and type 2 `diabetes.

Joshua Hawkins, BGR, 8 Dec. 2021 The researchers said the findings mean sildenafil, commonly used to treat erectile dysfunction and a type of high blood pressure, should be studied as a possible treatment for Alzheimer’s.

Robert Hart, Forbes, 6 Dec. 2021 The maximum dose of sildenafil (Viagra) is 100 milligrams.

Dr. Keith Roach, oregonlive, 7 Apr. 2021 See More

Medical Definition

sildenafil

noun

sil·den·a·fil sil-ˈden-ə-ˌfil How to pronounce sildenafil (audio)

: a drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ chiefly to treat erectile dysfunction in males and hypertension of the lungs

Note: Sildenafil inhibits a phosphodiesterase enzyme that degrades cyclic GMP. Higher levels of cyclic GMP in the body promote relaxation of smooth muscle, which allows for increased blood flow to the lungs to lower blood pressure and to the corpus cavernosum to produce an erection during sexual arousal. Sildenafil is marketed under the trademark Viagra to treat erectile dysfunction and under the trademark Revatio to treat pulmonary arterial hypertension.

单词	sildenafil
释义	sildenafil noun sil·den·a·fil sil-ˈde-nə-ˌfil : a drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection Note: Sildenafil is marketed under the trademarks Revatio and Viagra. Example Sentences Recent Examples on the Web The most common drugs, such as sildenafil (Viagra), work mostly on blood vessels but also have effects on raising both testosterone levels and estrogen levels in men. Dr. Keith Roach, oregonlive, 15 Apr. 2022 Doctors have indeed been using sildenafil in some cases to treat PAH. Bruce Y. Lee, Forbes, 18 Apr. 2022 The interaction between nitrates and sildenafil can lower blood pressure to dangerous levels, the FDA warns. Chris Smith, BGR, 7 Mar. 2022 The capsules were tested and found to contain sildenafil, the active ingredient in Viagra and other prescription medications used to treat erectile dysfunction in men. Elainie Barraza, orlandosentinel.com, 1 Feb. 2022 According to a new study, patients who took sildenafil, most commonly known as the drug Viagra, were less likely to suffer from Alzheimer’s disease. Joshua Hawkins, BGR, 8 Dec. 2021 Feixiong Cheng, a senior author on the study, says that the use of sildenafil helped reduce the likelihood of Alzheimer’s in individuals with coronary artery disease, hypertension, and type 2 `diabetes. Joshua Hawkins, BGR, 8 Dec. 2021 The researchers said the findings mean sildenafil, commonly used to treat erectile dysfunction and a type of high blood pressure, should be studied as a possible treatment for Alzheimer’s. Robert Hart, Forbes, 6 Dec. 2021 The maximum dose of sildenafil (Viagra) is 100 milligrams. Dr. Keith Roach, oregonlive, 7 Apr. 2021 See More Word History Etymology perhaps by alteration and recombination of letters from sulfonyl, phenyl, and pyrimidine First Known Use 1995, in the meaning defined above Medical Definition sildenafil noun sil·den·a·fil sil-ˈden-ə-ˌfil : a drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ chiefly to treat erectile dysfunction in males and hypertension of the lungs Note: Sildenafil inhibits a phosphodiesterase enzyme that degrades cyclic GMP. Higher levels of cyclic GMP in the body promote relaxation of smooth muscle, which allows for increased blood flow to the lungs to lower blood pressure and to the corpus cavernosum to produce an erection during sexual arousal. Sildenafil is marketed under the trademark Viagra to treat erectile dysfunction and under the trademark Revatio to treat pulmonary arterial hypertension.
随便看	mononitrate mononitrated mononitration mononitro monont mononuclear mononuclear phagocyte system mononuclear phagocytic system mononuclears mononucleate mononucleated mononucleoses mononucleosis mononucleotide mononucleotides mononychous monoolefin monoolefinic monoousian monoousious monopack monoparental monopectinate monopersulfuric acid monopetalous

sildenafil

noun

Example Sentences

Word History

Medical Definition

noun