单词 | prodrug |
释义 | prodrugnoun pro·drug ˈprō-ˌdrəg plural prodrugs : a pharmacologically inactive substance that is converted in the body (as by enzymatic action) into a pharmacologically active drug … an enzyme that transforms an inactive drug molecule, or prodrug, into an active anticancer agent. One source of the variability is the metabolism of clopidogrel, which is a prodrug requiring biotransformation to generate its active metabolite. … an orally administered prodrug of ganciclovir that provides improved bioavailability. |
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