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单词	prodrug
释义	prodrug noun pro·​drug ˈprō-ˌdrəg  plural prodrugs : a pharmacologically inactive substance that is converted in the body (as by enzymatic action) into a pharmacologically active drug … an enzyme that transforms an inactive drug molecule, or prodrug, into an active anticancer agent. Scientific American Cancer Smart One source of the variability is the metabolism of clopidogrel, which is a prodrug requiring biotransformation to generate its active metabolite. Jessica L. Mega … an orally administered prodrug of ganciclovir that provides improved bioavailability. Bernard A. Schwetz Word History First Known Use 1968, in the meaning defined above Medical Definition prodrug noun pro·​drug ˈprō-ˌdrəg  : a pharmacologically inactive substance that is the modified form of a pharmacologically active drug to which it is converted (as by enzymatic action) in the body One source of the variability is the metabolism of clopidogrel, which is a prodrug requiring biotransformation to generate its active metabolite. Jessica L. Mega et al., The Journal of the American Medical Association
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