sclerosis
noun
scle·ro·sis sklə-ˈrō-səs 
1
: pathological hardening of tissue especially from overgrowth of fibrous tissue or increase in interstitial tissue
also : a disease characterized by sclerosis
2
: an inability or reluctance to adapt or compromise
political sclerosis
Example Sentences
Recent Examples on the Web One culprit for permitting sclerosis is the National Environmental Policy Act (NEPA), a 1970 law that imposes environmental reviews. 
The Editorial Board, WSJ, 29 July 2022 Multiple sclerosis is a central nervous system disease that affects the brain and spinal cord. Beth Krietsch, SELF, 22 July 2022 Lawmakers would do well to advance policies that would cure the agency's sclerosis. Sally Pipes, Forbes, 18 July 2022 A year later, scientists reported that pathological TDP-43 was also present in the brains of people with Alzheimer’s disease and hippocampal sclerosis, a disease associated with pathological changes in the hippocampus. Diana Kwon, Scientific American, 13 July 2022 More widely, the failure will speak to the sclerosis of American governance. Robinson Meyer, The Atlantic, 15 June 2022 Multiple sclerosis is a potentially disabling disease of the brain and spinal cord. Ben Thomas | Bthomas@al.com, al, 27 May 2022 Robert Dallek, a historian and biographer of Lyndon B. Johnson, said such sclerosis had ebbed and flowed in the past. New York Times, 30 May 2022 Multiple sclerosis treatments, which cost between $8,000 and $11,000 in the mid-1990s, averaged $60,000 a year by 2015 and reached $80,000 by 2020. Billy Kenber, STAT, 14 May 2022 See More
The Editorial Board, WSJ, 29 July 2022 Multiple sclerosis is a central nervous system disease that affects the brain and spinal cord. Beth Krietsch, SELF, 22 July 2022 Lawmakers would do well to advance policies that would cure the agency's sclerosis. Sally Pipes, Forbes, 18 July 2022 A year later, scientists reported that pathological TDP-43 was also present in the brains of people with Alzheimer’s disease and hippocampal sclerosis, a disease associated with pathological changes in the hippocampus. Diana Kwon, Scientific American, 13 July 2022 More widely, the failure will speak to the sclerosis of American governance. Robinson Meyer, The Atlantic, 15 June 2022 Multiple sclerosis is a potentially disabling disease of the brain and spinal cord. Ben Thomas | Bthomas@al.com, al, 27 May 2022 Robert Dallek, a historian and biographer of Lyndon B. Johnson, said such sclerosis had ebbed and flowed in the past. New York Times, 30 May 2022 Multiple sclerosis treatments, which cost between $8,000 and $11,000 in the mid-1990s, averaged $60,000 a year by 2015 and reached $80,000 by 2020. Billy Kenber, STAT, 14 May 2022 See More Word History
Etymology
Middle English sclirosis tumor, from Medieval Latin, from Greek sklērōsis hardening, from sklēroun to harden, from sklēros
First Known Use
1846, in the meaning defined at sense 1
Phrases Containing sclerosis
Medical Definition
sclerosis
noun
scle·ro·sis sklə-ˈrō-səs
plural scleroses -ˌsēz
1
: a pathological condition in which a tissue has become hard and which is produced by overgrowth of fibrous tissue and other changes (as in arteriosclerosis) or by increase in interstitial tissue and other changes (as in multiple sclerosis)
called also hardening
2
: any of various diseases characterized by sclerosis —usually used in combination see arteriosclerosis, multiple sclerosis, myelosclerosis
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- get the measure of someone
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- get the message
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- get the nod
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- get the push
- get the runaround
- get the sack
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- get the worst of it
- get the wrong idea
- get the/this show on the road
- get there
- get this show on the road