单词	reading frame
释义	reading frame noun : a sequence of nucleotide triplets that is potentially translatable into a polypeptide and that is determined by the placement of a codon that initiates translation Example Sentences Recent Examples on the Web According to a study published in April 2020, mutations identified in the nonstructural protein NSP6 and open reading frame Orf10 likely prevent autophagosomes from delivering material to the lysosome. William A. Haseltine, Forbes, 7 Sep. 2021 It is synthesized as part of two much longer polypeptides, the product of the initial long open reading frame (orf1a), and from the orf1b, the orf1ab polypeptide. William A. Haseltine, Forbes, 4 June 2021 Further mutations to the nucleocapsid protein and open reading frame eight likely increase the virus’s virulence, as similar mutations have been seen in other variants. William A. Haseltine, Forbes, 18 Mar. 2021 For instance, Lanjuan noted a mutation in the open reading frame three at position 251 (G251V). William A. Haseltine, Forbes, 3 Mar. 2021 Word History First Known Use 1961, in the meaning defined above Medical Definition reading frame noun read·​ing frame ˈrēd-iŋ-  : any of the three possible ways of reading a sequence of nucleotides as a series of triplets see open reading frame
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