roofie
noun
roof·ie ˈrü-fē 
slang
: a tablet of a powerful benzodiazepine sedative and hypnotic drug C16H12FN3O3 that is not licensed for medical use in the U.S. but is used illicitly
Example Sentences
Recent Examples on the Web There have been wearable alarm systems, female condoms with teeth, and roofie-detecting nail polish. 
Jess Mchugh, Fortune, 19 Mar. 2020
Jess Mchugh, Fortune, 19 Mar. 2020 Word History
Etymology
probably by shortening & alteration from Rohypnol, a trademark name for the drug
First Known Use
1994, in the meaning defined above
Medical Definition
roofie
noun
roof·ie ˈrü-fē
plural roofies
slang
: a tablet of flunitrazepam used illicitly