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单词 amantadine
释义

amantadine

noun

aman·​ta·​dine ə-ˈman-tə-ˌdēn How to pronounce amantadine (audio)
: a drug used especially as the hydrochloride C10H17N·HCl to prevent infection (as by an influenza virus) by interfering with virus penetration into host cells

Example Sentences

Recent Examples on the Web The antiviral drug amantadine, for instance, was originally developed for influenza, but was repurposed as a Parkinson's therapy. Annette Bakker, Fortune, 5 July 2021 His main approach has been to target the mutation in the M2 channel that created resistance to amantadine and rimantadine. Neil Savage, Scientific American, 18 Sep. 2019 What’s more, the flu virus has developed resistance to oseltamivir and to an older drug, amantadine. Kai Kupferschmidt, Science | AAAS, 23 Oct. 2019 Nearly all the viruses in circulation around the globe had a mutation that rendered amantadine and rimantadine—the two adamantanes used to treat flu, which work by blocking a particular step in viral replication—completely useless. Neil Savage, Scientific American, 18 Sep. 2019 There are only two other classes of flu drugs, neuraminidase inhibitors (drugs like Tamiflu, Relenza, Rapivab) and the adamantane drugs (amantadine and rimantadine). Helen Branswell, STAT, 27 June 2018 Influenza viruses developed resistance long ago to the first two antiviral flu drugs, amantadine and rimantadine. NBC News, 26 June 2018 See More

Word History

Etymology

International Scientific Vocabulary amantad- (alteration of adamantane, C10H16) + amine

First Known Use

1964, in the meaning defined above

Medical Definition

amantadine

noun

aman·​ta·​dine ə-ˈmant-ə-ˌdēn How to pronounce amantadine (audio)
: a drug administered orally especially in the form of its hydrochloride C10H17N·HCl to prevent infection (as by the virus causing influenza A) by interfering with virus penetration into host cells and in the treatment of Parkinson's disease see symmetrel
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更新时间:2024/11/12 4:52:54