单词 | T cell receptor |
释义 | T cell receptornoun variants or T-cell receptor plural T cell receptors or T-cell receptors : an antigen receptor on the surface of a T cell that is composed of two transmembrane polypeptide chains covalently linked by disulfide bonds and that initiates T cell activation upon binding with a specific antigenic peptide fragment combined with a major histocompatibility complex molecule and displayed on the surface of an antigen-presenting cell … the T cell receptor actually recognizes not a solitary peptide but a complex consisting of a peptide and the surrounding region of the class I MHC molecule. Thierry Boon … the T-cell receptor … acts as the antigen receptor for T cells one of whose principal functions is to recognize and destroy virus-infected cells … Carl Branden et al. —abbreviation TCR |
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