单词	leukodystrophy
释义	leukodystrophy noun leu·​ko·​dys·​tro·​phy ˌlü-kō-ˈdi-strə-fē  plural leukodystrophies : any of several genetically determined diseases characterized by progressive degeneration of myelin in the brain, spinal cord, and peripheral nerves Example Sentences Recent Examples on the Web The couple’s children were born with metachromatic leukodystrophy (MLD), which causes muscle weakness, progressive loss of vision and eventual paralysis. Diane Moca, Chicago Tribune, 3 Sep. 2022 Metachromatic leukodystrophy, or MLD, is a rare, hereditary disease that leads to premature death. Priscilla Totiyapungprasert, The Arizona Republic, 5 Sep. 2020 Metachromatic leukodystrophy is the result of a genetic mutation, and leads to a breakdown of the protective covering around nerve cells and nerve fibers, known as myelin. Lisa Schencker, chicagotribune.com, 15 Nov. 2019 More recently, Evelyn Chizzo had been diagnosed with leukodystrophy, which is a rare genetic disease that affects the brain and nervous system. Rich Mayor, chicagotribune.com, 5 Oct. 2019 Pennsylvania is one of the few states in the U.S. where someone diagnosed with metachromatic leukodystrophy gets fast-tracked for Medicaid. Maria Kefalas, STAT, 2 Dec. 2019 The four-year-old has a rare disease called metachromatic leukodystrophy that could rob him of the ability to walk, sit and hold up his own head within the next year. Chicago Tribune Staff, chicagotribune.com, 18 Nov. 2019 After further testing, he was diagnosed with metachromatic leukodystrophy in July of this year. Lisa Schencker, chicagotribune.com, 15 Nov. 2019 Doctors knew Massimo suffered from a type of leukodystrophy, a genetic disorder of the central nervous system that destroys the brain’s white matter. Wired, 30 Aug. 2019 See More Word History First Known Use 1960, in the meaning defined above Medical Definition leukodystrophy noun leu·​ko·​dys·​tro·​phy variants or chiefly British leucodystrophy ˌlü-kō-ˈdis-trə-fē  plural leukodystrophies : any of several inherited diseases (as adrenoleukodystrophy) characterized by progressive degeneration of myelin in the brain, spinal cord, and peripheral nerves
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