单词	APC
释义	APC 1 of 2 noun ˌā-(ˌ)pē-ˈsē  : an armored vehicle used to transport military personnel APC 2 of 2 abbreviation 1 activated protein C Normally, a molecule called activated protein C, or APC, prevents clots from becoming too large by inactivating coagulation factor V. Jane E. Brody 2 antigen-presenting cell In order to trigger helper T cells, exogenous protein antigens must be taken up by antigen-presenting cells (APC) and processed into peptides that bind to MHC class II molecules. Paola Panina-Bordignon et al. Word History Etymology Noun armored personnel carrier First Known Use Noun 1952, in the meaning defined above Medical Definition APC 1 of 2 noun ˌā-ˌpē-ˈsē  : a tumor suppressor gene that in a defective form tends to be associated with a high risk of colorectal cancer Germ-line APC mutations give rise to familial adenomatous polyposis, an inherited cancer-predisposition syndrome in which more than 100 adenomatous polyps can develop; in carriers of the mutant gene, the risk of colorectal cancer by the age of 40 years is almost 100%. Sanford D. Markowitz and Monica M. Bertagnolli, The New England Journal of Medicine APC 2 of 2 abbreviation 1 activated protein C Normally, a molecule called activated protein C, or APC, prevents clots from becoming too large by inactivating coagulation factor V. Jane E. Brody, The New York Times 2 antigen-presenting cell When a T cell binds to such an APC, the T cell multiplies and launches an attack on cells that display the telltale protein-MHC complex—cells infected by a virus, foreign skin cells, or whatever. Sarah Richardson, Discover 3 aspirin, phenacetin, and caffeine The now-banned ingredient phenacetin, once widely used in APC (aspirin-phenacetin-caffeine) tablets, was found to contribute heavily to kidney disease. Melva Weber, Vogue
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