: a group, ion, or molecule coordinated to a central atom or molecule in a complex
Example Sentences
Recent Examples on the WebThese drugs, especially intravenous zoledronic acid (and the antibody to RANK ligand, denosumab), have been game-changers in patients with breast and other cancers that spread to bone. Dr. Keith Roach, oregonlive, 9 Aug. 2022 As a transmembrane protein, STING has two main domains: a transmembrane domain and cytoplasmic ligand-binding domain. William A. Haseltine, Forbes, 21 Apr. 2022 Electron density maps revealed that the remdesivir metabolite GS-441524 was the only ligand that showed binding in the crystal structures. William A. Haseltine, Forbes, 4 June 2021 One common example of a ligand is found in siderophores, chemical compounds that bacteria secrete to break down iron particles. Emily Underwood, Smithsonian Magazine, 3 Jan. 2020 The uranium molecule complex is a coordination compound, meaning a metal center with ligands surrounding it. Caroline Delbert, Popular Mechanics, 13 Jan. 2020 The secret is using nontoxic silicon nanocrystals and molecule glues called ligands. Caroline Delbert, Popular Mechanics, 3 Dec. 2019 Geoff Burnstock (University College London) discovered purinergic signaling in 1972, and has been characterizing the nucleotide and nucleoside ligands, their receptors and their biology ever since. Bradley J. Fikes, sandiegouniontribune.com, 26 May 2017 Last year one of Schelter's postdocs synthesized a three-armed molecule, called a tripodal ligand. Nelson Ching, National Geographic, 10 June 2016 See More
Word History
Etymology
Latin ligandus, gerundive of ligare
First Known Use
1949, in the meaning defined above
Medical Definition
ligand
noun
li·gand ˈlig-ənd ˈlīg-
: a group, ion, or molecule coordinated to a central atom or molecule in a complex