单词	graft-versus-host disease
释义	graft-versus-host disease noun graft-ver·​sus-host disease ˈgraft-ˌvər-səs-ˈhōst-  : a potentially fatal bodily condition that results when T cells from a tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues Example Sentences Recent Examples on the Web Above-average levels of these cells were also associated with better survival and less graft-versus-host disease in transplant patients. Kate Ann Markey, The Conversation, 13 July 2022 Up to 50% of patients who receive a stem cell transplant develop graft-versus-host disease. Kate Ann Markey, The Conversation, 13 July 2022 Patients with the highest levels of MAIT cells had the lowest incidence of graft-versus-host disease. Kate Ann Markey, The Conversation, 13 July 2022 Tinkov resigned as Tinkoff Bank’s chairman in 2020 after being diagnosed with acute leukemia and is battling graft-versus-host disease following a bone marrow transplant. Derek Saul, Forbes, 3 May 2022 The donor’s immune cells can attack the recipient’s body, a condition called graft-versus-host disease, or GVHD. Max G. Levy, Wired, 10 Feb. 2022 Dietrich Beelen, a transplant doctor at the University of Duisburg-Essen in Germany, was interested in using MSCs to treat a patient with severe graft-versus-host disease (GVHD). Michael Eisenstein, Scientific American, 17 June 2020 In July, Kadmon secured U.S. approval for Rezurock, a new treatment for chronic graft-versus-host disease — a debilitating immune condition that can affect as many as half of the blood cancer patients who undergo bone marrow transplants. Adam Feuerstein, STAT, 11 Sep. 2021 But finding a matching cell donor can be difficult, and a transplant can lead to graft-versus-host disease, a potentially deadly condition in which donor cells attack a patient’s cells. Kelly Servick, Science | AAAS, 11 Aug. 2021 See More Word History First Known Use 1965, in the meaning defined above Medical Definition graft-versus-host disease noun : a bodily condition that results when T cells from a usually allogeneic tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues, that affects especially the skin, gastrointestinal tract, and liver with symptoms including skin rash, fever, diarrhea, liver dysfunction, abdominal pain, and anorexia, and that may be fatal —abbreviation GVHD called also graft-versus-host reaction
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