单词	DNA methylation
释义	DNA methylation noun : the enzymatically controlled addition of a methyl group to a nucleotide base (such as cytosine in eukaryotes) in a molecule of DNA that plays a role in regulating gene expression (as by the inhibition of genetic transcription) When a methyl group attaches to a specific spot on a gene—a process called DNA methylation—it can change the gene's expression, turning it off or on, dampening it or making it louder. John Cloud A handful of drugs that affect DNA methylation already exist, and are being used to treat cancers in which faulty gene labeling plays a role. Helen Pilcher A process called DNA methylation sets down "marks" on bits of DNA and is typically thought to squelch gene expression. Sarah Baldauf DNA methylation is a mark on genomic DNA made by addition of methyl groups to cytosine bases … Adrian Bird Word History First Known Use 1963, in the meaning defined above Medical Definition DNA methylation noun : the enzymatically controlled methylation of a nucleotide base (as cytosine in eukaryotes) in a molecule of DNA that plays a role in suppressing gene expression
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