| Acronym | Definition |
|---|
| HPU➣Harry Potter Universe (online roleplay) |
| HPU➣Hawaii Pacific University |
| HPU➣High Point University |
| HPU➣High Performance Unload (IBM) |
| HPU➣Hydraulic Power Unit |
| HPU➣Howard Payne University (Brownwood, TX) |
| HPU➣Handheld Programming Unit |
| HPU➣High Power Unit |
| HPU➣Himachal Pradesh University (India) |
| HPU➣High Pressure Unit (various companies) |
| HPU➣Health Protection Unit (UK) |
| HPU➣Hewlett Packard University (various locations) |
| HPU➣Hebei Polytechnic University (Hebei, China) |
| HPU➣Homeless Persons Unit (UK) |
| HPU➣Hydraulic Pumping Unit |
| HPU➣Heat Pump Unit |
| HPU➣Hydrogen Production Unit |
| HPU➣Haemopyrrollactamuria (vitamin deficiency) |
| HPU➣Has Passed Urine |
| HPU➣High Priority Unit |
| HPU➣Hydrothermal Processing Unit |
| HPU➣Hull Processing Unit (Bradley Fighting Vehicle A3) |
| HPU➣Hour Per Unit |