| 释义 |
heparin
hep·a·rin H0153800 (hĕp′ər-ĭn)n.1. An acidic glycosaminoglycan found especially in lung and liver tissue and having the ability to slow the clotting of blood, used as a drug in the treatment of thrombosis. Also called unfractionated heparin.2. Any of several anticoagulants, such as enoxaparin, that are derived from this compound by depolymerization and have a lower molecular weight and somewhat different pharmacological properties. Also called low-molecular-weight heparin.
[Late Latin hēpar, liver (from Greek; see yē̆kwr̥ in Indo-European roots) + -in.]heparin (ˈhɛpərɪn) n (Biochemistry) a polysaccharide, containing sulphate groups, present in most body tissues: an anticoagulant used in the treatment of thrombosis[C20: from Greek hēpar the liver + -in] ˈheparinˌoid adjhep•a•rin (ˈhɛp ə rɪn)
n. a polysaccharide present in animal tissues, esp. the liver, that has anticoagulant properties and is used to prevent or dissolve blood clots. [1915–20; < Greek hêpar liver + -in1] Thesaurus| Noun | 1. | heparin - a polysaccharide produced in basophils (especially in the lung and liver) and that inhibits the activity of thrombin in coagulation of the blood; it (trade names Lipo-Hepin and Liquaemin) is used as an anticoagulant in the treatment of thrombosis and in heart surgeryLipo-Hepin, Liquaeminanticoagulant, anticoagulant medication, decoagulant - medicine that prevents or retards the clotting of bloodpolyose, polysaccharide - any of a class of carbohydrates whose molecules contain chains of monosaccharide molecules |
Translationsheparin
heparin (hĕp`ərĭn), anticoagulantanticoagulant
, any of several substances that inhibit blood clot formation (see blood clotting). Some anticoagulants, such as the coumarin derivatives bishydroxycoumarin (Dicumarol) and warfarin (Coumadin) inhibit synthesis of prothrombin, a clot-forming substance, and other
..... Click the link for more information. produced by cells in many animals. A polysaccharide, heparin is found in the human body and occurs in greatest concentration in the tissues surrounding the capillaries of the lungs and the liver. The substance, extracted from animal tissues, is used clinically to delay blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
..... Click the link for more information. .heparin[′hep·ə·rən] (biochemistry) An acid mucopolysaccharide acting as an antithrombin, antithromboplastin, and antiplatelet factor to prolong the clotting time of whole blood; occurs in a variety of tissues, most abundantly in liver. heparin
heparin [hep´ah-rin] 1. an acid mucopolysaccharide present in many tissues, especially the liver and lungs, and having potent anticoagulant properties. It also has lipotrophic properties, promoting transfer of fat from blood to the fat depots by activation of the enzyme lipoprotein lipase.2. a mixture of active principles capable of prolonging blood clotting time, obtained from domestic animals; used in the prophylaxis and treatment of clotting disorders, such as thrombophlebitis, embolism" >pulmonary embolism, coagulation" >disseminated intravascular coagulation, acute myocardial infarction, or stroke syndrome, and to prevent clotting during extracorporeal circulation, blood transfusion, and blood sampling.heparin lock a type of intermittent intravenous device for the administration of heparin. It does not require a continuous flow of fluids; the intravenous fluid flow can be disconnected and the heparin lock filled with a heparin solution that maintains patency of the needle.  Two types of heparin or saline lock sets. From Lammon et al., 1995.hep·a·rin (hep'ă-rin), An anticoagulant principle that is a component of various tissues (especially liver and lung) and mast cells in humans and several mammalian species; its principal and active constituent is a glycosaminoglycan composed of d-glucuronic acid and d-glucosamine, both sulfated, in 1,4-α linkage, of molecular weight between 6,000 and 20,000. In conjunction with a serum protein cofactor (the so-called heparin cofactor), heparin acts as an antithrombin and an antiprothrombin. Synthetic preparations are commonly used in therapeutic anticoagulation. It also enhances activity of "clearing factors" (lipoprotein lipases). Synonym(s): heparinic acidheparin (hĕp′ər-ĭn)n. An acidic glycosaminoglycan found especially in lung and liver tissue and having the ability to slow the clotting of blood, used as a drug in the treatment of thrombosis.heparin Hematology A sulfated glycosaminoglycan anticoagulant that inhibits activated factors IXa, Xa, XIa, XIIa and thrombin, ↓ local anti-thrombin-III, promoting its inactivation by neutrophil elastase; interaction of heparin with endothelial cells results in displacement of platelet factor 4, which inactivates heparin Indications Thromboembolism, CAD, post acute MI, PTE Monitoring Titrate heparin so that aPTT is 1.5-2.0-fold normal Side effects Hemorrhage, thrombocytopenia, osteoporosis, skin necrosis, alopecia, hypersensitivity, hypoaldosteronism. See Low-molecular weight heparin. hep·a·rin (hep'ăr-in) An anticoagulant that is a component of various tissues (especially liver and lung) and mast cells. Its principal active constituent is a glycosaminoglycan composed of d-glucuronic acid and d-glucosamine. In conjunction with a serum protein cofactor (the so-called heparin cofactor), heparin acts as an antithrombin and an antiprothrombin by preventing platelet agglutination and consequent thrombus formation. heparin A complex polysaccharide organic acid found mainly in lung and liver tissue. Heparin is thought to bind to THROMBIN and antithrombin in plasma thereby assisting in their combination and interfering with the cascade of reactions that end in blood clotting (coagulation). From the Greek hepar , the liver. The drug is on the WHO official list. Heparin is widely used as an anticoagulant under brand names such as Calciparine, Canusal, Hepsal, Monoparin and Multiparin. See also LOW MOLECULAR WEIGHT HEPARIN.heparin a mucopolysaccharide molecule produced in the liver and some white blood-cells that acts as an anticoagulant, inhibiting the transformation of prothrombin to thrombin, a vital stage in BLOOD CLOTTING.HeparinAn organic acid that occurs naturally in the body and prevents blood clots. Heparin is also made synthetically and can be given as a treatment when required.Mentioned in: Coagulation Disorders, Hypercoagulation Disorders, Partial Thromboplastin Time, Puerperal Infection, Thyroid Function TestsSee HP
See HPheparin
Related to heparin: Heparin induced thrombocytopeniaSynonyms for heparinnoun a polysaccharide produced in basophils (especially in the lung and liver) and that inhibits the activity of thrombin in coagulation of the bloodSynonymsRelated Words- anticoagulant
- anticoagulant medication
- decoagulant
- polyose
- polysaccharide
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