hyperimmunoglobulin M syndrome

hyperimmunoglobulin M syndrome

Hyper-IgM syndrome Immunology An X-R immunodeficiency Clinical Recurrent bacterial infections–eg, otitis media, pneumonia or opportunistic infections, recurrent neutropenia, lymphoid hyperplasia, neoplasia at an early age, and autoimmune phenomena Lab ↓/absent IgG, IgA, IgE; normal/↑ IgM, IgD