hyperinsulinaemic hypoglycaemia type 5

hyperinsulinaemic hypoglycaemia type 5

An autosomal dominant condition (OMIM:609968) characterised by persistent hypoglycaemia in infancy due to defective negative feedback regulation of insulin secretion by low serum glucose levels.
 
Molecular pathology
Defects of INSR cause hyperinsulinaemic hypoglycaemia type 5.