| 释义 |
gramicidin
gram·i·ci·din G0218500 (grăm′ĭ-sīd′n)n. An antibiotic substance consisting of a mixture of several closely related polypeptides, produced by the soil bacterium Bacillus brevis and used topically to treat infections caused by certain gram-positive bacteria.
[gram(-positive) + -cid(e) + -in.]gramicidin (ˌɡræmɪˈsaɪdɪn) or gramicidin Dn (Pharmacology) an antibiotic used in treating local Gram-positive bacterial infections: obtained from the soil bacterium Bacillus brevis[C20: from Gram(-positive) + -cid(e) + -in]Thesaurus| Noun | 1. | gramicidin - an antibiotic produced by a soil bacterium; used chiefly as an antiseptic in treating local infections produced by Gram-positive bacteriaantibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"antiseptic - a substance that destroys micro-organisms that carry disease without harming body tissues |
Translationsgramicidin
gramicidin (grăm'ĭsīd`ən), antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
..... Click the link for more information. obtained from the bacterial species Bacillus brevis, which is found in soil. Gramicidin is particularly effective against gram-positive bacteria (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
..... Click the link for more information. ). Because the drug is highly toxic, it cannot be administered internally and so is used only on the skin as a lotion or ointment. It is used primarily in the treatment of infected surface wounds, and in eye, nose, and throat infections. In 1939 the American microbiologist René Dubos isolated the substance tyrothricin and later showed that it was composed of two substances, gramicidin and tyrocidine. These were the first antibiotics to be manufactured commercially.Gramicidin a medicinal preparation of the antibiotic group, bacteriostatic and bactericidal against streptococci and staphylococci, the causative microorganisms of anaerobic infections, and other microbes. Gramicidin is applied locally as a solution or paste in the treatment of suppurative and inflammatory diseases, ulcers, and bedsores, as well as in the form of a paste as a contraceptive. gramicidin[‚gram·ə′sīd·ən] (microbiology) A polypeptide antibacterial antibiotic produced by Bacillus brevis ; active locally against gram-positive bacteria. gramicidin
gramicidin [gram″ĭ-si´din] an antibiotic produced by Bacillus brevis, applied topically in pyodermic, ocular, and other localized infections due to susceptible gram-positive organisms. It is also one of the two major components of tyrothricin, the other being tyrocidine.gram·i·ci·din (gram'i-sī'din), One of a group of polypeptide antibiotics produced by Bacillus brevis that are primarily bacteriostatic in action against gram-positive cocci and bacilli. Commercial preparations contain several gramicidins known as gramicidin A, B, C, and D; gramicidin S (for Soviet) is cyclic, the others are linear.gramicidin (grăm′ĭ-sīd′n)n. An antibiotic produced by the soil bacterium Bacillus brevis and used to treat infections caused by certain gram-positive bacteria.gram·i·ci·din (gram'i-sī'din) Polypeptide antibiotic that is bacteriostatic in action against gram-positive cocci and bacilli. gramicidin An antibiotic used externally in ointments and creams, often in conjunction with the antibiotics NEOMYCIN and FRAMYCETIN and with CORTICOSTEROIDS. It is too toxic for internal use. Brand names of various combinations with other drugs are Adcortyl, Graneodin, Neosporin, Sofradex, Soframycin and Tri-Adcortyl.antibiotic 1. Pertaining to the ability to destroy or inhibit other living organisms. 2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.gram·i·ci·din (gram'i-sī'din) One of a group of polypeptide antibiotics produced by Bacillus brevis that are primarily bacteriostatic in action against gram-positive cocci and bacilli. gramicidin
Related to gramicidin: framycetinWords related to gramicidinnoun an antibiotic produced by a soil bacteriumRelated Words- antibiotic
- antibiotic drug
- antiseptic
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