| Acronym | Definition |
|---|
| HSL➣Hue, Saturation, Lightness |
| HSL➣Health Sciences Library (various universities) |
| HSL➣Hormone-Sensitive Lipase |
| HSL➣High Speed Link |
| HSL➣Hessisches Statistisches Landesamt (German) |
| HSL➣High Speed Launch (British powerboat; UK) |
| HSL➣Hue Saturation Lightness |
| HSL➣Host Service Location |
| HSL➣Hybrid Silicon Laser |
| HSL➣Health and Safety Laboratory (United Kingdom) |
| HSL➣Health and Safety Law (various locations) |
| HSL➣Heat Seal Lacquer (various companies) |
| HSL➣Harwell Subroutine Library |
| HSL➣Highly Sensitive List (goods) |
| HSL➣Hybrid Solar Lighting |
| HSL➣High School Liaison (various locations) |
| HSL➣Hoge Snelheids Lijn (Dutch train) |
| HSL➣Helicopter Antisubmarine Squadron Light (US Navy) |
| HSL➣HERMES Softlab |
| HSL➣Hazardous Substance List |
| HSL➣Hardship Letter (immigration) |
| HSL➣Hindustan Shipyard Ltd (India) |
| HSL➣Holy Spirit Led |
| HSL➣Home School Link |
| HSL➣Hardware Simulation Laboratory (US NASA) |
| HSL➣Helicopter Antisubmarine Warfare Light |
| HSL➣Holland Sociaal Liggend (Dutch: Holland Social Landscape; cycling club) |
| HSL➣Hydrographic-Survey Launch |
| HSL➣Hypertonic Saline |
| HSL➣Hindustan Steel Limited (India) |
| HSL➣Helicopter Anti-Submarine Warfare Squadron Light |
| HSL➣Hypermedia Synchronization Language (Digital Research Corporation) |
| HSL➣Hue, Saturation, and Luminescence (less common; probably incorrect) |
| HSL➣Health Service Laboratory |
| HSL➣Helicopter Sling Load (cargo transport) |
| HSL➣Home Station Launch |
| HSL➣Huntington Station Library (Huntington Station, NY) |
| HSL➣Hazard Significant Level |
| HSL➣Humane Society of Lewisville, TX |
| HSL➣Helvetas Sri Lanka |
| HSL➣Hazardous Substance Location (New Zealand HSNO regulations) |
