单词 | hereditary nonpolyposis colon cancer |
释义 | hereditary nonpolyposis colon cancerhereditary nonpolyposis colon cancerLynch I syndrome Oncology A relatively distinct AD form of cancer that may account for 5-10% of all colorectal CA Clinical Family Hx of colorectal CA at relatively young age, primarily of proximal colon, tendency toward multiple primary tumors; HNPCC may be ssociated with extracolonic tumors–eg, of endometrium Diagnosis Amsterdam criteria. See Amsterdam criteria, Colorectal cancerhMSH-2. Cf Familial adenomatous polyposis. |
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