| 单词 | hereditary preneoplasia |
| 释义 | hereditary preneoplasiahereditary preneoplasiaA general term for a neoplastic substrate related to a syndrome Examples Phakomatoses–eg, Cowden's disease, multiple exostoses, Peutz-Jegher syndrome, von Hippel-Lindau syndrome, neurofibromatosis, tuberous sclerosis, genodermatoses–eg, albinism, dyskeratosis congenita, epidermodysplasia verruciformis, polydysplastic epidermolysis bullosa, Werner syndrome, xeroderma pigmentosa, chromosome instability syndromes and immune deficiencies–eg, ataxia-telangiectasia, CVID, Wiskott-Aldrich syndrome, X-linked agammaglobulinemia and X-linked lymphoproliferative syndrome. See Cancer families, Common variable immunodeficiency. Cf One-hit, two-hit model. |
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